Ordering Recommendation

General initial test for immunobullous diseases. Test includes IgG and IgA BMZ antibodies (pemphigoid, epidermolysis bullosa acquisita, linear IgA disease) and IgG and IgA cell surface antibodies (IgG and IgA pemphigus subtypes). Consider ordering concurrently with Bullous Pemphigoid Antigens (180 kDa and 230 kDa), IgG (0092566) and Collagen Type VII Antibody IgG by ELISA (2010905) for suspected pemphigoid or EBA and/or Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG (0090649) for suspected pemphigus. For more sensitive and specific testing for pemphigoid and EBA or pemphigus, refer to Basement Membrane Zone Antibody Panel (3001410) or Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650).

Mnemonic
EPITHELIAL
Methodology

Indirect Immunofluorescence
(Indirect Fluorescent Antibody)

Performed

Varies

Reported

4-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or lipemic specimens.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data



No compliance statements are in use for this test.

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History
N/A
Components
Component Test Code* Component Chart Name LOINC
0090298 Epithelial Skin Antibodies
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Epithelial Skin Antibody