Collagen Type VII Antibody, IgG by ELISA
Ordering Recommendation
Use to monitor disease in patients diagnosed with epidermolysis bullosa acquisita (EBA) or bullous lupus erythematosus with increased IgG type VII collagen antibody levels.
For initial diagnosis, including discrimination among various immunobullous diseases, and assessment of disease progression/changes and intermittent monitoring, the Immunobullous Disease Antibody Panel (3001409) or Basement Membrane Zone Antibody Panel (3001410) is preferred.
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated/Ambient
Hemolyzed or lipemic specimens. Plasma.
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
3-9 days
Reference Interval
By report
Interpretive Data
Refer to report.
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
CPT Codes
83516
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2010906 | Collagen Type VII Antibody IgG by ELISA | |
2010907 | EER Collagen Type VII Ab IgG, by ELISA |
Aliases
- bullous lupus erythematosus
- bullous systemic lupus erythematosus
- Collagen Type VII Antibody IgG by ELISA
- dermal basement membrane zone antibodies with split skin substrate
- epidermolysis bullosa acquisita
- salt-split skin floor antibodies
- subepithelial immunobullous disease
- type VII collagen antibodies