Ordering Recommendation
Use to monitor disease in patients diagnosed with epidermolysis bullosa acquisita (EBA) or bullous lupus erythematosus with increased IgG type VII collagen antibody levels.
For initial diagnosis, including discrimination among various immunobullous diseases, and assessment of disease progression/changes and intermittent monitoring, the Immunobullous Disease Antibody Panel (3001409) or Basement Membrane Zone Antibody Panel (3001410) is preferred.
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Varies
Reported
7-14 days
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens. Plasma.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Reference Interval
By report
Interpretive Data
Refer to report
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
Hotline History
CPT Codes
83516
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2010906 | Collagen Type VII Antibody IgG by ELISA | |
2010907 | EER Collagen Type VII Ab IgG, by ELISA |
Aliases
- bullous lupus erythematosus
- Collagen Type VII Antibody IgG by ELISA
- dermal basement membrane zone antibodies on split skin substrate
- epidermolysis bullosa acquisita
- salt-split skin floor antibodies
- type VII collagen antibodies