Desmoglein 1 and Desmoglein 3 (Pemphigus) Antibodies, IgG by ELISA

0090649
copy
 

Copy Utility


emailprint
Example Reports
Enhanced Report
Negative
Positive

Icon

Clinical Information for Immunodermatology (Serum Testing)

Ordering Recommendation

Use to monitor disease in patients diagnosed with various pemphigus variants and increased IgG desmoglein 1 and/or IgG desmoglein 3 antibodies; antibody levels correlate with disease activity. 

For initial diagnosis, Pemphigus Antibody Panel, IgG (0090650) has greater diagnostic sensitivity and specificity and is preferred in the assessment of disease progression/changes and for intermittent monitoring of IgG pemphigus variants. For more comprehensive evaluation, consider Immunobullous Disease Antibody Panel (3001409). For diagnosing rare types of pemphigus, refer to Pemphigus Antibodies, IgA by IIF (0092106) and Paraneoplastic Pemphigus (Paraneoplastic Autoimmune Multiorgan Syndrome) Antibody Screening Panel (0092107).

For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.

Mnemonic

IGG DESMOG

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

3-9 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or lipemic specimens. Plasma.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Performed by non-ARUP Laboratory

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/14/2022
X
X
X
X
N/A

CPT Codes

83516 x2

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0090653 Desmoglein 1 and 3 Antibodies, IgG 19146-0
2010912 EER Desmoglein 1 and 3 Antibodies, IgG 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG
  • desmosomal protein antibodies
  • desmosome antibodies
  • endemic pemphigus
  • fogo selvagem
  • ICS antibodies
  • intercellular IgG/IgA dermatosis
  • intercellular substance antibodies
  • pemphigus
  • pemphigus erythematosus
  • pemphigus foliaceus
  • pemphigus vegetans
  • pemphigus vulgaris
Desmoglein 1 and Desmoglein 3 (Pemphigus) Antibodies, IgG by ELISA