• Monitor disease in patient previously diagnosed with pemphigus and increased IgG desmoglein 1 and/or 3 antibodies; antibody levels correlate with disease activity. Consider ordering with Epithelial Cell Surface Antibody IgG (0090266).
• If used to screen for pemphigus, this test has decreased sensitivity and specificity when compared to Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650).
• For initial diagnosis and monitoring disease, Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650) is preferred.
• For diagnosing rare types of pemphigus, refer Pemphigus Antibody IgA (0092106) and Paraneoplastic Pemphigus Antibody Screen (0092107).
Enzyme-Linked Immunosorbent Assay
Plain red or serum separator tube.
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
No compliance statements are in use for this test.
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
|Component Test Code*||Component Chart Name||LOINC|
|0090653||Desmoglein 1 and 3 Antibodies, IgG||19146-0|
|2010912||EER Desmoglein 1 and 3 Antibodies, IgG||11526-1|