Bullous Pemphigoid (BP180 and BP230) Antibodies, IgG by ELISA
Ordering Recommendation
Use to monitor disease in patients diagnosed with pemphigoid and increased IgG BP180 and/or BP230 antibody levels. For initial pemphigoid diagnosis that discriminates among immunobullous diseases and for assessment of disease progression/changes and intermittent monitoring, the Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Antibody Panel (3001409) is preferred. In a relevant clinical setting, consider Pemphigoid Gestationis, Complement-Fixing Basement Membrane Antibodies (Herpes Gestationis Factor) (0092283).
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)
Refrigerated/Ambient
Hemolyzed or lipemic specimens. Plasma.
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
3-9 days
Reference Interval
By report
Interpretive Data
Refer to report.
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
CPT Codes
83516 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0092568 | Bullous Pemphigoid Antigens, IgG | 57911-0 |
2010915 | EER Bullous Pemphigoid Antigens, IgG |
Aliases
- BP Antigen 1
- BP Antigen 2
- BP180 and BP230
- bullous pemphigoid
- Bullous Pemphigoid (180 & 230) Antigens
- bullous pemphigoid antigen 1 or BPAg1
- bullous pemphigoid antigen 2 or BPAg2
- collagen type 17
- epidermal basement membrane zone (roof) antibodies on split skin substrate (salt split skin)
- hemidesmosomal protein antibodies
- hemidesmosome antibodies
- herpes gestationis
- NC16A
- pemphigoid gestationis
- pemphigoid variants, IgG BP 180 and BP 230
- salt-split skin roof antibodies
- type XVII collagen, collagen type XVII