Bullous Pemphigoid (BP180 and BP230) Antibodies, IgG by ELISA
Ordering Recommendation
Use to monitor disease in patients diagnosed with pemphigoid and increased IgG BP180 and/or BP230 antibody levels. For initial pemphigoid diagnosis that discriminates among immunobullous diseases and for assessment of disease progression/changes and intermittent monitoring, the Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Antibody Panel (3001409) is preferred. In a relevant clinical setting, consider Pemphigoid Gestationis, Complement-Fixing Basement Membrane Antibodies (Herpes Gestationis Factor) (0092283).
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)
Refrigerated/Ambient
Hemolyzed or lipemic specimens. Plasma.
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
3-9 days
Reference Interval
By report
Interpretive Data
Refer to report.
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
Hotline History
CPT Codes
83516 x2
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0092568 | Bullous Pemphigoid Antigens, IgG | 57911-0 |
| 2010915 | EER Bullous Pemphigoid Antigens, IgG |
Aliases
- BP180 and BP230
- BP Antigen 1
- BP Antigen 2
- bullous pemphigoid
- Bullous Pemphigoid (180 & 230) Antigens
- bullous pemphigoid antigen 1 or BPAg1
- bullous pemphigoid antigen 2 or BPAg2
- collagen type 17
- epidermal basement membrane zone (roof) antibodies on split skin substrate (salt split skin)
- hemidesmosomal protein antibodies
- hemidesmosome antibodies
- herpes gestationis
- NC16A
- pemphigoid gestationis
- pemphigoid variants, IgG BP 180 and BP 230
- salt-split skin roof antibodies
- type XVII collagen
- collagen type XVII
















