Ordering Recommendation

Use to monitor disease in patients diagnosed with pemphigoid and increased IgG BP180 and/or BP230 antibody levels. For initial pemphigoid diagnosis that discriminates among immunobullous diseases and for assessment of disease progression/changes and intermittent monitoring, the Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Antibody Panel (3001409) is preferred. In a relevant clinical setting, consider Pemphigoid Gestationis, Complement-Fixing Basement Membrane Antibodies (Herpes Gestationis Factor) (0092283).

For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.

Mnemonic

BP180 230G

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

3-11 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or lipemic specimens. Plasma.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Performed by non-ARUP Laboratory

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History

N/A

CPT Codes

83516 x2

Components

Component Test Code* Component Chart Name LOINC
0092568 Bullous Pemphigoid Antigens, IgG 57911-0
2010915 EER Bullous Pemphigoid Antigens, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • BP 180 and BP 230
  • BP Antigen 1
  • BP Antigen 2
  • bullous pemphigoid
  • Bullous Pemphigoid (180 & 230) Antigens
  • bullous pemphigoid antigen 1 or BPAg1
  • bullous pemphigoid antigen 2 or BPAg2
  • collagen type 17
  • hemidesmosomal protein antibodies
  • hemidesmosome antibodies
  • herpes gestationis
  • NC16A
  • pemphigoid gestationis
  • pemphigoid variants, IgG BP 180 and BP 230
  • type XVII collagen, collagen type XVII
Bullous Pemphigoid (BP180 and BP230) Antibodies, IgG by ELISA