Ordering Recommendation

Use to monitor disease in patients diagnosed with pemphigoid and increased IgG BP180 and/or BP230 antibody levels; IgG BP180 antibody levels correlate with disease activity in some patients.

For initial diagnosis and assessment of disease progression/changes and intermittent monitoring, preferred test is Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Panel, Epithelial (3001409).

Epithelial Basement Membrane Zone Antibody IgG (0092056) can be used to determine the involvement of IgG basement membrane zone antibodies and pattern of reactivity on split skin substrate. Consider other basement membrane zone antibody-associated disease testing (ie, Epithelial Basement Membrane Zone Antibody IgA [0092057], Collagen Type VII Antibody IgG by ELISA [2010905], or Herpes Gestationis Factor (Complement-Fixing Basement Membrane Zone Antibody IgG) [0092283]).

For initial pemphigoid diagnosis, Basement Membrane Zone Antibody Panel (3001410) or  Immunobullous Disease Panel, Epithelial (3001409) is preferred.


BP180 230G


Semi-Quantitative Enzyme-Linked Immunosorbent Assay




3-11 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Hemolyzed or lipemic specimens.


Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History


CPT Codes

83516 x2


Component Test Code* Component Chart Name LOINC
0092568 Bullous Pemphigoid Antigens, IgG 57911-0
2010915 EER Bullous Pemphigoid Antigens, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • BP 180 and BP 230
  • BP Antigen 1
  • BP Antigen 2
Bullous Pemphigoid Antigens (180 kDa and 230 kDa), IgG