Ordering Recommendation

Use as initial testing panel to aid in the diagnosis of and distinguishing among skin and mucous membrane disorders that present with blistering, erosions, eczema, pruritus, and/or urticaria, including pemphigoid, pemphigoid variants, epidermolysis bullosa acquisita (EBA), linear IgA bullous dermatosis, linear IgA disease variants, bullous lupus erythematosus and IgG-pemphigus subtypes. Use for assessment of suspected epithelial antibody-associated immunobullous diseases that may be nonspecific, may not be clinically distinguishable, may present with overlapping epithelial antibody expression, and/or may be indicated by concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572).

Immunobullous Disease Panel, Epithelial, (3001409) components include Epithelial Basement Membrane Zone IgG Antibodies (0092056), Epithelial Basement Membrane Zone IgA Antibodies (0092057), Bullous Pemphigoid (180&230) IgG Antibodies (0092566), Collagen Type VII Antibody IgG (2010905), IgG Epithelial Cell Surface Antibodies (0090266), IgG Desmoglein 1 & Desmoglein 3 (0090649), and IgA (Cell Surface) Pemphigus (0092106).

Mnemonic
IMBULDZPAN
Methodology

Indirect Fluorescent Antibody/Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

4-9 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or Lipemic specimens. Plasma

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Not Applicable

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History
N/A
CPT Codes

88346; 88350 x5; 83516 x5

Components
Component Test Code* Component Chart Name LOINC
3001665 Immunobullous Disease Panel
3001666 EER Immunobullous Disease Panel
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Immunobullous Disease Panel, Epithelial