Basement Membrane Zone Antibody Panel
Ordering Recommendation
Use as the preferred initial diagnostic panel for suspected basement membrane zone antibody-associated skin and mucous membrane disorders that present with blistering, erosions, eczema, urticaria, pruritus, and/or mucositis. May be indicated by concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572).
Alternatively, order the comprehensive Immunobullous Disease Antibody Panel (3001409) for initial serum diagnostic assessment of epithelial antibody-associated diseases, pemphigoid, pemphigus, and their variants.
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
Methodology
Semi-Quantitative Indirect Immunofluorescence (IIF)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
4-9 days
New York DOH Approval Status
Specimen Required
Plain Red or Serum Separator Tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens. Plasma
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Reference Interval
By report
Interpretive Data
Refer to report
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
Hotline History
CPT Codes
88346; 88350 x3; 83516 x3
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001664 | Basement Membrane Zone Ab Panel | 63566-4 |
3001667 | EER Basement Membrane Zone Ab Panel |
Aliases
- basement membrane zone antibody-associated disease
- bullous lupus erythematosus
- bullous pemphigoid
- bullous pemphigoid antigen 1 or BPAg1
- bullous pemphigoid antigen 2 or BPAg2
- childhood immunobullous disease
- chronic bullous disease of childhood
- cicatricial pemphigoid
- collagen type 17
- dermal basement membrane zone antibodies on split skin substrate
- epidermal basement membrane zone antibodies on split skin substrate
- epidermolysis bullosa acquisita (EBA)
- hemidesmosomal protein antibodies
- hemidesmosome antibodies
- IgA variant epidermolysis bullosa acquisita (EBA)
- IgG/IgA basement membrane zone antibodies
- immunobullous disease of childhood
- linear IgA bullous dermatosis (LABD)
- linear IgA disease (LAD)
- linear IgG/IgA bullous dermatosis; mixed immunobullous disease of childhood
- mucous membrane pemphigoid
- NC16A
- ocular cicatricial pemphigoid
- pemphigoid variants
- salt-split skin floor antibodies
- salt-split skin roof antibodies
- salt-split skin test
- subepithelial immunobullous disease
- type VII collagen antibodies
- type XVII collagen, collagen type XVII