Ordering Recommendation

Use as the preferred initial diagnostic panel for skin and mucous membrane disorders that present with blistering, erosions, eczema, pruritus, and/or urticaria from suspected basement membrane zone antibody-associated disease (ie, pemphigoid, epidermolysis bullosa acquisita [EBA],  linear IgA disease, bullous lupus erythematosus). May be indicated by concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572).

Alternatively, order Immunobullous Disease Panel, Epithelial (3001409) for initial diagnostic assessment.

Components include Epithelial Basement Membrane Zone IgG Antibodies (0092056), Epithelial Basement Membrane Zone IgA Antibodies (0092057), Bullous Pemphigoid (180&230) IgG Antibodies (0092566), and Collagen Type VII Antibody IgG (2010905).

Mnemonic
BMZ AB PAN
Methodology

Indirect Fluorescent Antibody/Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

4-9 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or Lipemic specimens. Plasma

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Not Applicable

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History
N/A
CPT Codes

88346; 88350 x2; 83516 x3

Components
Component Test Code* Component Chart Name LOINC
3001664 Basement Membrane Zone Ab Panel
3001667 EER Basement Membrane Zone Ab Panel
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Basement Membrane Zone Antibody Panel