Basement Membrane Zone Antibody Panel
Ordering Recommendation
Use as the preferred initial diagnostic panel for suspected basement membrane zone antibody-associated skin and mucous membrane disorders that present with blistering, erosions, eczema, urticaria, pruritus, and/or mucositis. May be indicated by concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572).
Alternatively, order the comprehensive Immunobullous Disease Antibody Panel (3001409) for initial serum diagnostic assessment of epithelial antibody-associated diseases, pemphigoid, pemphigus, and their variants.
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
New York DOH Approval Status
Specimen Required
Plain Red or Serum Separator Tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens. Plasma
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Indirect Immunofluorescence (IIF)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
4-9 days
Reference Interval
By report
Interpretive Data
Refer to report
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
Hotline History
CPT Codes
88346; 88350 x3; 83516 x3
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001664 | Basement Membrane Zone Ab Panel | 63566-4 |
3001667 | EER Basement Membrane Zone Ab Panel |
Aliases
- basement membrane zone antibody-associated disease
- bullous lupus erythematosus
- bullous pemphigoid
- bullous pemphigoid antigen 1 or BPAg1
- bullous pemphigoid antigen 2 or BPAg2
- childhood immunobullous disease
- chronic bullous disease of childhood
- cicatricial pemphigoid
- collagen type 17
- dermal basement membrane zone antibodies on split skin substrate
- epidermal basement membrane zone antibodies on split skin substrate
- epidermolysis bullosa acquisita (EBA)
- hemidesmosomal protein antibodies
- hemidesmosome antibodies
- IgA variant epidermolysis bullosa acquisita (EBA)
- IgG/IgA basement membrane zone antibodies
- immunobullous disease of childhood
- linear IgA bullous dermatosis (LABD)
- linear IgA disease (LAD)
- linear IgG/IgA bullous dermatosis; mixed immunobullous disease of childhood
- mucous membrane pemphigoid
- NC16A
- ocular cicatricial pemphigoid
- pemphigoid variants
- salt-split skin floor antibodies
- salt-split skin roof antibodies
- salt-split skin test
- subepithelial immunobullous disease
- type VII collagen antibodies
- type XVII collagen, collagen type XVII