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Basement Membrane Zone Antibody Panel
Ordering Recommendation
Use as the preferred initial diagnostic panel for suspected basement membrane zone antibody-associated skin and mucous membrane disorders that present with blistering, erosions, eczema, urticaria, pruritus, and/or mucositis. May be indicated by concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572).
Alternatively, order the comprehensive Immunobullous Disease Antibody Panel (3001409) for initial serum diagnostic assessment of epithelial antibody-associated diseases, pemphigoid, pemphigus, and their variants.
New York DOH Approval Status
Specimen Required
Plain Red or Serum Separator Tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated/Ambient
Hemolyzed or lipemic specimens. Plasma
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Indirect Immunofluorescence (IIF)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
3-9 days
Reference Interval
By report
Interpretive Data
Refer to report.
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
Hotline History
CPT Codes
88346; 88350 x3; 83516 x3
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3001664 | Basement Membrane Zone Ab Panel | 63566-4 |
| 3001667 | EER Basement Membrane Zone Ab Panel |
Aliases
- linear IgA bullous dermatosis
- salt-split skin test
- subepithelial immunobullous disease
- type VII collagen antibodies
- mucous membrane pemphigoid
- IgG/IgA basement membrane zone antibodies
- linear IgA disease
- linear IgA/IgG bullous dermatosis
- mixed immunobullous disease of childhood
- atypical epithelial antibody-associated disease
- basement membrane zone antibody-associated disease
- Brunsting-Perry cicatricial pemphigoid
- Brunsting-Perry pemphigoid
- bullous lupus erythematosus
- bullous pemphigoid
- bullous pemphigoid antigen 1 or BPAg1
- bullous pemphigoid antigen 2 or BPAg2, NC16A
- bullous systemic lupus erythematosus
- childhood immunobullous disease
- chronic bullous disease of childhood
- cicatricial pemphigoid
- collagen type 17
- collagen type XVII
- dermal basement membrane zone (floor) antibodies with split skin substrate
- epidermal basement membrane zone (roof) antibodies with split skin substrate
- epidermolysis bullosa acquisita (EBA)
- epithelial antibody-associated disease
- hemidesmosomal protein antibodies
- hemidesmosome antibodies
- IgA mucous membrane pemphigoid
- IgA variant epidermolysis bullosa acquisita (EBA)
- ocular cicatricial pemphigoid
- pemphigoid variants
- salt-split skin floor antibodies
- mixed epithelial antibody-associated disease
- immunobullous disease of childhood
- type XVII collagen, collagen type XVII
- salt-split skin roof antibodies
- indirect fluorescence assay
- indirect fluorescent antibody (IFA)
- indirect immunofluorescent assay
