Ordering Recommendation

Use as preferred serum antibody panel for initial assessment and disease monitoring in IgG-variant pemphigus. Testing should be clinically supported and/or correlated with concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572).

Pemphigus vulgaris and pemphigus foliaceus are the most common types of IgG-variant pemphigus with blistering and erosive disease affecting skin and mucous membranes.

Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3. To order individual component tests, refer to Epithelial Cell Surface Antibody IgG (0090266) or Epithelial Skin Antibody (0090299) and Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG (0090649).

To assess for pemphigus along with other immunobullous diseases, order concurrently with Basement Membrane Zone Antibody Panel (3001410). Also order with Pemphigus Antibody IgA (0092106).

Alternatively, order Immunobullous Disease Panel, Epithelial (3001409). Note that this test is included as part of the Immunobullous Disease Panel, Epithelial.




Semi-Quantitative Indirect Fluorescent Antibody (IFA)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay




4-9 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Plain red or serum separator tube.

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Hemolyzed or lipemic specimens.


Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History


CPT Codes

88346; 88350; 83516 x2


Component Test Code* Component Chart Name LOINC
0090651 Pemphigus Antibody Panel, IgG 21352-0
2010913 EER Pemphigus Antibody Panel, IgG 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG