Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG
• Preferred panel for initial assessment and disease monitoring in IgG-variant pemphigus. Pemphigus vulgaris and pemphigus foliaceus are the most common types of pemphigus with blistering and erosive disease affecting skin and mucous membranes.
• Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3. To order individual component tests, refer to Epithelial Skin Antibody (0090299) and/or Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG (0090649).
• To screen for pemphigus along with other possible immunobullous diseases, order concurrently with Basement Membrane Zone Antibody Panel (3001410); this panel includes IGA and IgG BMZ antibodies, BP180 and BP230 antibodies, IgG, and collagen VII antibodies, IgG. Also order with Pemphigus Antibody IgA (0092106), AND Cutaneous Direct Immunofluorescence, Biopsy (0092572).
• Alternatively, order Immunobullous Disease Panel, Epithelial (3001409), AND Cutaneous Direct Immunofluorescence, Biopsy (0092572). (Note that the Pemphigus Antibody Panel is included as part of the Immunobullous Disease Panel, Epithelial.)
Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody
Plain red or serum separator tube.
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
No compliance statements are in use for this test.
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
88346; 88350; 83516 x2
|Component Test Code*||Component Chart Name||LOINC|
|0090651||Pemphigus Antibody Panel, IgG||21352-0|
|2010913||EER Pemphigus Antibody Panel, IgG||11526-1|