Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (INACTIVE as of 11/15/21: Refer to 3004013 in the November Hotline)
Use as preferred serum antibody panel for initial assessment and disease monitoring in IgG-variant pemphigus. Testing should be clinically supported and/or correlated with concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572).
Pemphigus vulgaris and pemphigus foliaceus are the most common types of IgG-variant pemphigus with blistering and erosive disease affecting skin and mucous membranes.
Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3. To order individual component tests, refer to Epithelial Cell Surface Antibody IgG (0090266) or Epithelial Skin Antibody (0090299) and Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG (0090649).
Alternatively, order Immunobullous Disease Panel, Epithelial (3001409). Note that this test is included as part of the Immunobullous Disease Panel, Epithelial.
Semi-Quantitative Indirect Fluorescent Antibody (IFA)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
New York DOH Approval Status
Plain red or serum separator tube.
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
88346; 88350; 83516 x2
|Component Test Code*||Component Chart Name||LOINC|
|0090651||Pemphigus Antibody Panel, IgG||21352-0|
|2010913||EER Pemphigus Antibody Panel, IgG||11526-1|