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Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG
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Use as preferred serum antibody panel for initial assessment and disease monitoring in IgG-variant pemphigus. Testing should be clinically supported and/or correlated with concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572).
Pemphigus vulgaris and pemphigus foliaceus are the most common types of IgG-variant pemphigus with blistering and erosive disease affecting skin and mucous membranes.
Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3. To order individual component tests, refer to Epithelial Cell Surface Antibody IgG (0090266) or Epithelial Skin Antibody (0090299) and Desmoglein 1 and Desmoglein 3 Antibodies in Pemphigus, IgG (0090649).
To assess for pemphigus along with other immunobullous diseases, order concurrently with Basement Membrane Zone Antibody Panel (3001410). Also order with Pemphigus Antibody IgA (0092106).
Alternatively, order Immunobullous Disease Panel, Epithelial (3001409). Note that this test is included as part of the Immunobullous Disease Panel, Epithelial.
Semi-Quantitative Indirect Fluorescent Antibody (IFA)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Varies
4-9 days
Plain red or serum separator tube.
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
By report
Not Applicable
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
88346; 88350; 83516 x2
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0090651 | Pemphigus Antibody Panel, IgG | 21352-0 |
| 2010913 | EER Pemphigus Antibody Panel, IgG | 11526-1 |
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