Pemphigus Antibody Panel, IgG
Ordering Recommendation
Use as the preferred serum antibody panel to assess and monitor IgG-variant pemphigus (includes pemphigus foliaceus and pemphigus vulgaris), which present with blistering and erosive disease affecting skin and mucous membranes. Testing should be correlated with concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572).
To assess for other immunobullous diseases along with pemphigus, including the rare IgA pemphigus variant, order concurrently with serum Basement Membrane Zone Antibody Panel (3001410) and Pemphigus Antibodies, IgA by IIF (0092106). Alternatively, order Immunobullous Disease Antibody Panel (3001409).
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)
Refrigerated/ambient
Hemolyzed or lipemic specimens. Plasma.
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Indirect Immunofluorescence (IIF) / Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
3-9 days
Reference Interval
By report
Interpretive Data
Refer to report
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
CPT Codes
88346; 88350; 83516 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0090651 | Pemphigus Antibody Panel, IgG | 21352-0 |
2010913 | EER Pemphigus Antibody Panel, IgG | 11526-1 |
Aliases
- desmosomal protein antibodies
desmosome antibodies
endemic pemphigus
fogo selvagem
ICS antibodies
IgG pemphigus variant
IgG variant pemphigus
intercellular IgG/IgA dermatosis
intercellular substance antibodies
Pemphigus Antibody Panel - IgG Epithelial Cell Surface and Desmoglein 1 and Desmoglein 3 Antibodies
pemphigus erythematosus
pemphigus foliaceus
pemphigus vegetans
pemphigus vulgaris
prickle cell antibodies
Senear-Usher