If pursuing antibody testing to determine autoimmune diabetes mellitus, perform at least two antibody tests. In most cases, use glutamic acid decarboxylase antibody in combination with another antibody test. Other antibody tests include Glutamic Acid Decarboxylase Antibody (2001771), Insulin Antibody (0099228), Islet Cell Cytoplasmic Antibody, IgG (0050138), and Zinc Transporter 8 Antibody (2006196). Most useful to establish autoimmune etiology in previously diagnosed type 1 DM. Do not use to differentiate type 1 DM from type 2 DM, for most cases.
Quantitative Enzyme-Linked Immunosorbent Assay
Mon, Wed, Fri
Plain Red or Serum Separator Tube (SST).
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.35 mL)
Plasma. Specimens submitted in frozen Serum Separator Tubes (SST). Grossly hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
A value greater than or equal to 7.5 Units/mL is considered positive for IA-2 autoantibody.
This assay is intended for the quantitative determination of autoantibodies to Islet Antigen-2 (IA-2) in human serum. Results should be interpreted within the context of clinical symptoms.
|Component Test Code*||Component Chart Name||LOINC|
- Anti-IA2 Antibody
- IA-2 AB
- IA-2 Autoantibody
- Islet Antigen 2
- Islet Cell Antibody
- Islet Cell Antigen (ICA) 512
- Tyrosine Phosphatase-Like Protein Antibodies
- tyrosine phosphatase-related islet antigen 2