Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
If pursuing antibody testing to determine autoimmune diabetes mellitus, perform at least two antibody tests. In most cases, use glutamic acid decarboxylase antibody in combination with another antibody test. Other antibody tests include Glutamic Acid Decarboxylase Antibody (2001771), Insulin Antibody (0099228), Islet Cell Cytoplasmic Antibody, IgG (0050138), and Zinc Transporter 8 Antibody (2006196). Most useful to establish autoimmune etiology in previously diagnosed type 1 DM. Do not use to differentiate type 1 DM from type 2 DM, for most cases.
MnemonicUnique test identifier.
IA-2 AB
MethodologyProcess(es) used to perform the test.
Quantitative Enzyme-Linked Immunosorbent Assay
PerformedDays of the week the test is performed.
Mon, Wed, Fri
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
2-10 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Plain Red or Serum Separator Tube (SST).
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.35 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma. Specimens submitted in frozen Serum Separator Tubes (SST). Grossly hemolyzed, icteric, or lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
0.0-7.4 Units/mL
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
A value greater than or equal to 7.5 Units/mL is considered positive for IA-2 autoantibody.
This assay is intended for the quantitative determination of autoantibodies to Islet Antigen-2 (IA-2) in human serum. Results should be interpreted within the context of clinical symptoms.
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
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