Determine presence of antibodies to endogenous or exogenous insulin analogues. Testing not recommended for patients receiving insulin >2 weeks, as insulin antibody formation may occur.
If pursuing antibody testing to determine autoimmune diabetes mellitus (DM), perform at least two antibody tests. In most cases, use glutamic acid decarboxylase antibody in combination with another antibody test. Other antibody tests include Islet Antigen-2 (IA-2) Autoantibody (3001499), Glutamic Acid Decarboxylase Antibody (2001771), Islet Cell Cytoplasmic Antibody, IgG (0050138), and Zinc Transporter 8 Antibody (2006196). Do not use to differentiate type 1 DM from type 2 DM, for most cases.
Tue, Wed, Fri
New York DOH Approval Status
Serum separator tube or plain red.
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)
Plasma. Hemolyzed or lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months
Effective May 21, 2012
0.0-0.4 Kronus Units/mL
A value greater than 0.4 Kronus Units/mL is considered positive for Insulin Antibody. Kronus units are arbitrary.
Kronus Units = U/mL.
This assay is intended for the semi-quantitative determination of antibodies to endogenous insulin or antibodies to exogenous insulin in human serum. Antibodies to exogenous insulin therapies may be detected using this method. The magnitude of the measured result is not related to disease progression. Results should be interpreted within the context of clinical symptoms.
|Component Test Code*||Component Chart Name||LOINC|
- anti-insulin antibody
- Human Insulin Antibodies
- insulin AB
- Insulin Antibodies, Serum