Use to assess and monitor positive IgG basement membrane zone antibodies, including epidermal (roof) pattern, dermal (floor) pattern, and combined on split skin substrate in patients with pemphigoid and epidermolysis bullosa acquisita (EBA), especially those with normal IgG BP 180, IgG BP 230, and IgG type VII collagen antibody levels.
Consider ordering concurrently with Epithelial Basement Membrane Zone Antibody IgA (0092057), Bullous Pemphigoid Antigens (180 kDa and 230 kDa), IgG (0092566), and/or Collagen Type VII Antibody IgG by ELISA (2010905); alternatively, order Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Panel, Epithelial (3001409), which includes this testing.
Decreased diagnostic sensitivity and specificity when testing for pemphigoid and EBA compared with Basement Membrane Zone Antibody Panel (3001410) or for pemphigoid compared with Pemphigoid Antibody Panel (0092001).
Semi-Quantitative Indirect Fluorescent Antibody (IFA)
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
|Component Test Code*||Component Chart Name||LOINC|
|0092056||Epithelial BMZ Ab, IgG|