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Pemphigus Antibody IgA (INACTIVE as of 11/15/21: Refer to 3004012 in the November Hotline)
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Ordering Recommendation
Use to assess and monitor patients with possible IgA pemphigus, a rare disease with certain clinical and histopathologic subtypes. Testing should be clinically supported and/or correlated with concurrent Cutaneous Direct Immunofluorescence, Biopsy (0092572)
If other types of pemphigus are diagnostic considerations, order this test concurrently with Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650) or, for broader epithelial antibody testing, Immunobullous Disease Panel, Epithelial (3001409). Note that this test is included as part of the Immunobullous Disease Panel, Epithelial.
Mnemonic
Methodology
Semi-Quantitative Indirect Fluorescent Antibody (IFA)
Performed
Varies
Reported
3-7 days
Changed 05/09/05: 4-9 days
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Reference Interval
By report
Interpretive Data
Not Applicable
Note
The methodology is indirect immunofluorescence (IFA) of serum on substrates with known epidermal (epithelial) cell surface antigens (both intact human skin and monkey esophagus substrate). For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
CPT Codes
88346; 88350
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0092106 | Pemphigus Ab, IgA | 42936-5 |
Aliases
- IgA Pemphigus Antibodies
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