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Zinc Transporter 8 Antibody
2006196
Ordering Recommendation

• If pursuing antibody testing to determine autoimmune diabetes mellitus, perform at least 2 antibody tests. Other antibody tests include Glutamic Acid Decarboxylase Antibody (2001771), IA-2 Antibody (0050202), Insulin Antibody (0099228), and Islet Cell Cytoplasmic Antibody, IgG (0050138).
• Most useful to establish autoimmumne etiology in previously diagnosed type 1 DM.
• Do not use to differentiate type 1 versus type 2 DM, for most cases.

Mnemonic
ZNT8 AB
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Wed
Reported
1-8 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube or plain red.  
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma. Grossly hemolyzed or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 5 days; Refrigerated: 1 week; Frozen: 3 months  
Reference Interval
0.0-15.0 Kronus Units/mL
Interpretive Data
A value greater than 15.0 Kronus Units/mL is considered positive for ZnT8 antibody.
Kronus Units are arbitrary. Kronus Units=U/mL


Note
CPT Code(s)
86341
Components
Component Test Code*Component Chart NameLOINC
2006197Zinc Transporter 8 Antibody76651-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ZnT8
  • ZnT8 antibodies
  • ZnT8A