Feedback
Epithelial Basement Membrane Zone Antibody IgG
0092056
Ordering Recommendation
•Monitor disease in patient with pemphigoid or epidermolysis bullosa acquisita who has positive IgG BMZ antibodies by indirect immunofluorescence, either epidermal (roof) pattern or dermal (floor) pattern, on split skin substrate.
•Consider ordering concurrently with IgG antibody testing for bullous pemphigoid (BP180 & 230) antigens (0092566) and/or collagen type VII (2010905).
•May use to screen for pemphigoid and other immunobullous diseases; however, this test has decreased sensitivity and specificity when compared to the panel tests for pemphigus antibodies (0090650) or pemphigoid antibodies (0092001) and will not detect IgA BMZ antibodies.
Mnemonic
EBMZ IGG
Methodology
Indirect Immunofluorescence
(Indirect Fluorescent Antibody)
Performed
Varies
Reported
4-9 days  
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
  
Collect
Plain red or serum separator tube (SST).  
Specimen Preparation
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Hemolyzed or lipemic specimens.  
Remarks
  
Stability
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely  
Reference Interval
By report  
Interpretive Data
 
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
CPT Code(s)
88347 x2
Components
Component Test Code*Component Chart NameLOINC
0092056Epithelial BMZ Ab, IgG 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
 

Performed at UUHC-Immunodermatology