Not recommended in routine evaluation or management of diabetes mellitus (DM). Glutamic Acid Decarboxylase Antibody (GAD) (2001771
) and IA-2 Antibody (insulinoma antigen 2) (0050202
) recommended for initial screening of suspected cases of type 1 DM.
Semi-Quantitative Indirect Fluorescent Antibody
This test is New York DOH approved.
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
< 1:4 No antibody detected.
Islet cell antibodies (ICAs) are associated with type 1 diabetes (T1D), an autoimmune endocrine disorder. These antibodies may be present in individuals years before the onset of clinical symptoms. To calculate Juvenile Diabetes Foundation (JDF) units: multiply the titer x 5 (1:8 8 x 5 = 40 JDF Units).
|Component Test Code*||Component Chart Name|
|0050138||Islet Cell Cytoplasmic Antibody, IgG|
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
- Anti-Islet Cell Antibody
- beta cell
- Cytoplasmic Islet Cell Ab
- Islet Cell Ab IgG