Insulin Antibody
Ordering Recommendation

• Use to determine presence of antibodies to exogenous insulin analogues. Testing not recommended for patients receiving insulin >2 weeks, as insulin antibody formation may occur.
• If pursuing antibody testing to determine autoimmune diabetes mellitus, perform at least 2 antibody tests. In most cases, use glutamic acid decarboxylase antibody in combination with another antibody test. Other antibody tests include Glutamic Acid Decarboxylase Antibody (2001771), IA-2 Antibody (0050202), Islet Cell Cytoplasmic Antibody, IgG (0050138), and Zinc Transporter 8 Antibody (2006196).
• Do not use to differentiate type 1 DM from type 2 DM, for most cases.

Quantitative Radioimmunoassay
Tue, Wed, Fri
2-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube or plain red. 
Specimen Preparation
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Plasma. Hemolyzed or lipemic specimens. 
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months 
Reference Interval
Effective May 21, 2012

0.0-0.4 Kronus Units/mL
Interpretive Data
This assay quantitatively measures human serum autoantibodies to endogenous insulin or antibodies to exogenous insulin.
A value of greater than 0.4 Kronus Units/mL is considered positive for Insulin Antibody.
Kronus Units are arbitrary. Kronus Units=U/mL

Component Test Code*Component Chart NameLOINC
0098223Insulin Antibody8074-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • anti-insulin antibody
  • Human Insulin Antibodies
  • insulin AB
  • Insulin Antibodies, Serum