0092057
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Basement Membrane Zone (Epithelial) Antibodies, IgA by IIF

EBMZ IGA
Example Reports
Enhanced Report
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Clinical Information for Immunodermatology (Serum Testing)

Ordering Recommendation

Use to assess and monitor IgA basement membrane zone antibodies in patients with linear IgA disease, including linear IgA bullous dermatosis and chronic bullous disease of childhood, and IgA variant epidermolysis bullosa acquisita (EBA). Testing should be correlated with concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572). 

For initial linear IgA disease diagnosis, serum Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Antibody Panel (3001409) is preferred and offers a more comprehensive evaluation.

For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated: Ambient

Unacceptable Conditions

Hemolyzed or lipemic specimens. Plasma.

Remarks

As a general rule, serum specimens should be shipped to the laboratory as soon as possible.

Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.

Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Methodology

Semi-Quantitative Indirect Immunofluorescence (IIF)

Performed

Varies

Reported

4-9 days

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Performed by non-ARUP Laboratory

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/21/2023
X
N/A

CPT Codes

88346; 88350

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Components

Component Test Code* Component Chart Name LOINC
0092057 Epithelial BMZ Ab, IgA
3004035 EER Epithelial BMZ Ab, IgA 38440-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • linear IgA disease
  • mixed immunobullous disease of childhood
  • hemidesmosomal protein antibodies
  • mixed epithelial antibody-associated disease
  • salt-split skin test
  • subepithelial immunobullous disease
  • indirect fluorescence assay
  • atypical epithelial antibody-associated disease
  • immunobullous disease of childhood
  • indirect fluorescent antibody (IFA)
  • Epithelial Basement Membrane Zone Antibody IgA
  • linear IgG/IgA bullous dermatosis
  • IgA variant epidermolysis bullosa acquisita (EBA)
  • chronic bullous disease of childhood
  • epithelial antibody-associated disease
  • IgG/IgA basement membrane zone antibodies
  • childhood immunobullous disease
  • basement membrane zone antibody-associated disease
  • hemidesmosome antibodies
  • indirect immunofluorescent assay
  • linear IgA bullous dermatosis
Basement Membrane Zone (Epithelial) Antibodies, IgA by IIF