Basement Membrane Zone (Epithelial) Antibodies, IgA by IIF

0092057
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Clinical Information for Immunodermatology (Serum Testing)

Ordering Recommendation

Use to assess and monitor IgA basement membrane zone antibodies in patients with linear IgA disease, including linear IgA bullous dermatosis and chronic bullous disease of childhood, and IgA variant epidermolysis bullosa acquisita (EBA). Testing should be correlated with concurrent Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572). 

For initial linear IgA disease diagnosis, serum Basement Membrane Zone Antibody Panel (3001410) or Immunobullous Disease Antibody Panel (3001409) is preferred and offers a more comprehensive evaluation.

For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.

Mnemonic

EBMZ IGA

Methodology

Semi-Quantitative Indirect Immunofluorescence (IIF)

Performed

Varies

Reported

4-9 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain red or serum separator tube (SST).

Specimen Preparation

Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or lipemic specimens. Plasma.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Category

Performed by non-ARUP Laboratory

Note

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.

Hotline History

N/A

CPT Codes

88346; 88350

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Components

Component Test Code* Component Chart Name LOINC
0092057 Epithelial BMZ Ab, IgA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • atypical epithelial antibody-associated disease
  • basement membrane zone antibody-associated disease
  • childhood immunobullous disease
  • chronic bullous disease of childhood
  • epithelial antibody-associated disease
  • Epithelial Basement Membrane Zone Antibody IgA
  • hemidesmosomal protein antibodies
  • hemidesmosome antibodies
  • IgA variant epidermolysis bullosa acquisita (EBA)
  • IgG/IgA basement membrane zone antibodies
  • immunobullous disease of childhood
  • indirect fluorescence assay
  • indirect fluorescent antibody (IFA)
  • indirect immunofluorescent assay
  • linear IgA bullous dermatosis
  • linear IgA disease
  • linear IgG/IgA bullous dermatosis
  • mixed epithelial antibody-associated disease
  • mixed immunobullous disease of childhood
  • salt-split skin test
  • subepithelial immunobullous disease
Basement Membrane Zone (Epithelial) Antibodies, IgA by IIF