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Epithelial Cell Surface Antibody IgG
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Ordering Recommendation
Use to assess and monitor patients with positive IgG cell surface antibodies in pemphigus, especially in patients with normal IgG desmoglein 1 and IgG desmoglein 3 antibody levels.
Decreased diagnostic sensitivity and specificity when testing for pemphigus compared to Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650).
For initial pemphigus diagnostic testing, the preferred test is Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and Desmoglein 3 Antibodies, IgG (0090650) or Immunobullous Disease Panel, Epithelial (3001409).
Mnemonic
Methodology
Semi-Quantitative Indirect Fluorescent Antibody (IFA)
Performed
Varies
Reported
4-9 days
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Hemolyzed or lipemic specimens.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Reference Interval
By report
Interpretive Data
Not Applicable
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
CPT Codes
88346; 88350
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0090268 | Epithelial Cell Surface Ab IgG |
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