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Bullous Pemphigoid Antigens (180 kDa and 230 kDa), IgG
0092566
Ordering Recommendation

• Monitor disease in patient previously diagnosed with pemphigoid and increased antibodies for IgG BP 180 and/or BP 230; IgG BP 180 antibody levels correlate with disease activity. 
• For initial diagnosis and assessment of disease progression or changes, the preferred test is Basement Membrane Zone Antibody Panel (3001410), or Immunobullous Disease Panel, Epithelial (3001409). 
• Epithelial Basement Membrane Zone Antibody IgG (0092056) can be used to determine the involvement of IgG BMZ antibodies and pattern of reactivity on split skin substrate. Also consider other types of BMZ antibody-associated disease testing, (ie, Epithelial Basement Membrane Zone Antibody IgA (0092057), Collagen Type VII Antibody IgG by ELISA (2010905), or Herpes Gestationis Factor (Complement-Fixing Basement Membrane Zone Antibody IgG) (0092283)).

Mnemonic
BP180 230G
Methodology
Enzyme-Linked Immunosorbent Assay
Performed
Varies
Reported
3-11 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Plain red or serum separator tube (SST). 
Specimen Preparation
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Hemolyzed or lipemic specimens. 
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely 
Reference Interval
By report
Interpretive Data


Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
Hotline History
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Components
Component Test Code*Component Chart NameLOINC
0092568Bullous Pemphigoid Antigens, IgG57911-0
2010915EER Bullous Pemphigoid Antigens, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • BP 180 and BP 230
  • BP Antigen 1
  • BP Antigen 2