Bullous Pemphigoid Antigens (180 kDa and 230 kDa), IgG
Ordering Recommendation

• Monitor disease in patient previously diagnosed with pemphigoid and increased antibodies for IgG BP180 and/or BP230; IgG BP180 antibody levels correlate with disease activity.
• For initial diagnosis and assessment of disease progression or changes, the preferred test is Pemphigoid Antibody Panel - Epithelial Basement Membrane Zone Antibodies, IgG and IgA, BP180 and BP230 Antibodies, IgG (0092001).
• To determine the involvement of IgG BMZ antibodies and pattern of reactivity on split skin substrate, order with Epithelial Basement Membrane Zone Antibody IgG (0092056).
• Also, consider other types of BMZ antibody-associated disease testing, (i.e., Epithelial Basement Membrane Zone Antibody IgA (0092057), Collagen Type VII Antibody IgG by ELISA (2010905), or Herpes Gestationis Factor (Complement-Fixing Basement Membrane Zone Antibody IgG) (0092283)).

BP180 230G
Enzyme-Linked Immunosorbent Assay
3-11 days
New York DOH Approval Status
This test is New York DOH approved.
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Plain red or serum separator tube (SST). 
Specimen Preparation
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Hemolyzed or lipemic specimens. 
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely 
Reference Interval
By report
Interpretive Data

For specimens less than 0.5 mL, call the Immunodermatology Laboratory at (866) 266-5699.
CPT Code(s)
83516 x2
Component Test Code*Component Chart NameLOINC
0092568Bullous Pemphigoid Antigens, IgG57911-0
2010915EER Bullous Pemphigoid Antigens, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • BP 180 and BP 230
  • BP Antigen 1
  • BP Antigen 2

Performed at UUHC-Immunodermatology