3016639
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Red Blood Cell Antigen Genotyping, Fetal

RBCGENO FE
Example Reports
See Note

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Additional Technical Information

Ordering Recommendation

Fetal genotyping for 35 red blood cell antigens and phenotypic variants to assess risk for alloimmune hemolytic disease. This test does not assess for RhD; to test for RhD, refer to RhD Gene (RHD) Copy Number, Fetal (3016640).

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis

Performed

Varies

Reported

3-10 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

Fetal genotyping: Amniotic fluid
OR Cultured amniocytes: Two T-25 flasks at 80 percent confluency.
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.
AND Maternal cell contamination specimen: Lavender (K2EDTA), pink (K2EDTA), or yellow (ACD solution A or B).

Specimen Preparation

Genotyping: Transport 3 mL whole blood. (Min: 1 mL)
Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container. (Min: 5 mL)
Cultured amniocytes: Transport two T-25 flasks at 80 percent confluency filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Maternal cell contamination specimen: Transport 3 mL whole blood (Min: 1 mL)

Storage/Transport Temperature

Cultured amniocytes: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood or maternal cell contamination specimen: Refrigerated.

Unacceptable Conditions

Plasma or serum; collection of specimens in sodium heparin tubes. Frozen specimens in glass collection tubes.

Remarks

Maternal specimen is recommended for proper test interpretation if contamination of the fetal specimen from the mother is suspected. Order Maternal Cell Contamination.

Stability

Whole blood or maternal cell contamination specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month.
Fetal specimens: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reference Interval

Interpretive Data

Refer to report

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

Maternal specimen is recommended for proper test interpretation; order Maternal Cell Contamination, Maternal Specimen.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/21/2023
X
N/A

CPT Codes

0001U; 81265 Fetal Cell Contamination (FCC)

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0050548 Maternal Contamination Study Fetal Spec 59266-7
0050612 Maternal Contam Study, Maternal Spec 66746-9
3001055 Rh Antigen C/c
3001056 Rh Antigen E/e
3001057 Rh Antigen V/VS
3001058 Kell Antigen K/k
3001059 Kell Antigen Kpa/Kpb
3001060 Kell Antigen Jsa/Jsb
3001061 Duffy Antigen Fya/Fyb
3001062 Kidd Antigen Jka/Jkb
3001063 MNS Antigen MN
3001064 MNS Antigen S/s/U
3001065 Lutheran Antigen Lua/Lub
3001066 Dombrock Antigen Doa/Dob
3001067 Dombrock Antigen Hy
3001068 Dombrock Antigen Joa
3001069 Landsteiner-Wiener Antigen LWa/LWb
3001070 Diego Antigen Dia/Dib
3001071 Colton Antigen Coa/Cob
3001072 Scianna Antigen Sc1/Sc2
3001073 Hemoglobin S Antigen
3016643 RBC Antigen Genotyping, Fetal Specimen 31208-2
3016644 RBC Antigen Genotyping Fetal, Interp 50398-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Colton genotyping (Coa, Cob)
  • Diego genotyping (Dia, Dib)
  • Dombrock genotyping (Doa, Dob, Hy, Joa)
  • Duffy genotyping (Fya, Fyb, Fyb-67C)
  • Kell genotyping (K, k, Kpa, Kpb, Jsa, Jsb)
  • Kidd genotyping (Jka, Jkb)
  • Landsteiner-Wiener genotyping (LWa, LWb)
  • Lutheran genotyping (Lua, Lub)
  • MNS genotyping (M, N, S, s, U, Uvar, Uneg)
  • Rh genotyping (C, c, E, e, V, VS)
  • Scianna genotyping (Sc1, Sc2)
Red Blood Cell Antigen Genotyping, Fetal