RhD Gene (RHD) Copy Number, Fetal
Use to determine fetal RHD copy number(s) and assess the risk of alloimmune hemolytic disease. This test does not identify or distinguish between partial and weak RHD genotypes. For parental or neonatal testing, refer to RhD (RHD) Copy Number (0051368).
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis
New York DOH Approval Status
Fetal genotyping: Amniotic fluid
OR Cultured amniocytes : Two T-25 flasks at 80 percent confluency.
OR cultured CVS: Two T-25 flasks at 80 percent confluency.
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.
AND Maternal cell contamination specimen (see Remarks): Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container. (Min: 5 mL)
Cultured amniocytes AND cultured CVS: Transport two T-25 flasks at 80 percent confluency filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Maternal cell contamination specimen: Transport 3 mL whole blood (Min: 1 mL)
Whole blood (parental genotyping): Transport 3 mL whole blood. (Min: 1 mL)
Amniotic fluid, cultured amniocytes and cultured CVS: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood or maternal cell contamination specimen: Refrigerated.
Frozen specimens in glass collection tubes.
Maternal specimen is recommended for proper test interpretation if contamination of the fetal specimen from the mother is suspected. Order Maternal Cell Contamination. Patient History Form is available on the ARUP website or by contacting ARUP Client Services.
Amniotic fluid, cultured amniocytes and cultured CVS Fetal Specimen: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Whole blood or maternal cell contamination specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Refer to report.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Laboratory Developed Test (LDT)
Maternal specimen is recommended for proper test interpretation; order Maternal Cell Contamination, Maternal Specimen.
81403; 81265 Fetal Cell Contamination (FCC)
|Component Test Code*||Component Chart Name||LOINC|
|0050548||Maternal Contamination Study Fetal Spec||59266-7|
|0050612||Maternal Contam Study, Maternal Spec||66746-9|
|3016641||RhD Gene (RHD) Copy Number, Fetal Spec||31208-2|
|3016642||RhD Gene (RHD) Copy Number Fetal, Interp||50398-7|
- RHD Gene
- RHD genotyping