Ordering Recommendation
First-line serologic screening test for suspected Lyme disease. Positive or equivocal results must be confirmed by immunoblot.
Mnemonic
LYME PEP
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma, CSF. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 10 days; Frozen: 1 month
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
B. burgdorferi VlsE1/pepC10 Abs, ELISA | 0.90 IV or less |
Interpretive Data
Refer to report.
Component |
Interpretation |
---|---|
B. Burgdorferi VlsE1/pepC10 Abs, ELISA | 0.90 IV or less; Negative - VlsE1 and pepC10 antibodies to B. burgdorferi not detected. 0.91-1.09 IV; Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater; Positive - VlsE1 and pepC10 antibodies to B. burgdorferi detected. |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86618
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3003258 | B. burgdorferi VlsE1/pepC10 Abs, ELISA | 100711-1 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Lyme Disease
- Lyme Disease C6 Peptide Ab, ELISA
- VlsE Lipoprotein
- VlsE1/pepC10 Assay
Borrelia burgdorferi VlsE1/pepC10 Antibodies, Total by ELISA