Epidermal Transglutaminase (eTG/TG3) Antibody, IgA by ELISA
Ordering Recommendation
Use to assess and monitor dermatitis herpetiformis. Testing should be correlated with Direct Immunofluorescence, Tissue Biopsy (Cutaneous, Mucosal, Epithelial) (0092572). Because most patients with dermatitis herpetiformis have associated celiac disease, testing should be performed in conjunction with Celiac Disease Reflexive Cascade, Serum (3016817).
For initial diagnosis and assessment of disease progression/changes and to distinguish from other immunobullous diseases with epithelial antibodies, order concurrently with serum Immunobullous Disease Antibody Panel (3001409).
For more information about components, methodology, and specimen type, see the ARUP Immunobullous Disease Testing Comparison tool.
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)
Refrigerated/ambient
Hemolyzed or lipemic specimens. Plasma.
As a general rule, serum specimens should be shipped to the laboratory as soon as possible.
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Indefinitely
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Varies
Reported
7-21 days
Reference Interval
By report
Interpretive Data
Refer to report
Performed by non-ARUP Laboratory
Note
For specimens less than 0.5 mL, call the Immunodermatology Laboratory at 801-581-7139.
Hotline History
CPT Codes
83516
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2010903 | Epidermal Transglutaminase Ab IgA, ELISA | |
2010904 | EER Epidermal Transglutaminase Ab, IgA | 11502-2 |
Aliases
- Brocq-Duhring disease
- celiac disease
- celiac rash
- celiac sprue
- dermatitis herpetiformis
- dermatitis multiformis
- DH
- Duhring disease
- Duhring-Brocq disease
- EMA
- endomysial antibody
- Epidermal Transglutaminase (TG/TG3) Antibody, IgA by ELISA
- gluten rash
- gluten-sensitive enteropathy
- HLA-DQ2
- HLA-DQ8