Ordering Recommendation

Aids in the diagnosis of histoplasmosis. May also detect blastomycosis and coccidioidomycosis. Testing in conjunction with Histoplasma Antibodies by Complement Fixation and Immunodiffusion (0050627) and Histoplasma Antigen Quantitative by EIA, Serum (0092522) is recommended.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Random urine.

Specimen Preparation

Transfer 2 mL urine to an ARUP standard transport tube.

Storage/Transport Temperature


Unacceptable Conditions

Specimens other than urine. Urine in boric acid. Serum; refer to test Histoplasma Antigen by EIA, Serum (ARUP test code 0092522).


Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 2 weeks


Quantitative Enzyme Immunoassay




1-2 days

Reference Interval

Not Detected

Interpretive Data

Less than 0.4 ng/ml = Not Detected
0.4-0.7 ng/mL = Detected (below the limit of quantification)
0.8-24.0 ng/mL = Detected
Greater than 24.0 ng/mL = Detected (above the limit of quantification)

The quantitative range of this assay is 0.8-24.0 ng/mL. Antigen concentrations between 0.4-0.7 or >24.0 ng/mL fall outside the linear range of the assay and cannot be accurately quantified.

This EIA test should be used in conjunction with other diagnostic procedures, including microbiological culture, histological examination of biopsy samples, and/or radiographic evidence, to aid in the diagnosis of histoplasmosis.

Compliance Category

Modified FDA


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2006111 Histoplasma Galactomannan Ag Interp, Urn 44524-7
2006112 Histoplasma Galactomannan Ag Quant, Urn 48952-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • galactomannan
  • Histo
  • Histo Antigen
  • Histoag
  • Histoplasma capsulatum
  • histoplasmosis
Histoplasma Galactomannan Antigen Quantitative by EIA, Urine