Ordering Recommendation

Aid in the diagnosis of histoplasmosis. Recommend testing in conjunction with Histoplasma Antibodies by CF & ID (0050627) and Histoplasma Antigen Quantitative by EIA, Serum (0092522).

Mnemonic
HISTOGM U
Methodology

Quantitative Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 2 mL urine to an ARUP Standard Transport Tube.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimens other than urine. Urine in boric acid. Serum; refer to test Histoplasma Antigen by EIA, Serum (ARUP test code 0092522).

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Reference Interval

Not Detected

Interpretive Data

Less than 0.4 ng/ml = Not Detected
0.4-3.1 ng/mL = Detected (below the limit of quantification)
3.2-20.0 ng/mL = Detected
Greater than 20.0 ng/mL = Detected (above the limit of quantification)

The quantitative range of this assay is 3.2-20.0 ng/mL. Antigen concentrations between 0.4-3.1 or >20.0 ng/mL fall outside the linear range of the assay and cannot be accurately quantified.

This EIA test should be used in conjunction with other diagnostic procedures, including microbiological culture, histological examination of biopsy samples, and/or radiographic evidence, to aid in the diagnosis of histoplasmosis.

Compliance Category

Modified FDA

Note
Hotline History
N/A
CPT Codes

87385

Components
Component Test Code* Component Chart Name LOINC
2006111 Histoplasma Galactomannan Ag Interp, Urn 44524-7
2006112 Histoplasma Galactomannan Ag Quant, Urn 48952-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Histoplasma capsulatum
Histoplasma Galactomannan Antigen Quantitative by EIA, Urine