Ordering Recommendation

Aid in the diagnosis of histoplasmosis. Recommend testing in conjunction with Histoplasma Antibodies by CF & ID (0050627) and Histoplasma Antigen Quantitative by EIA, Serum (0092522).


Quantitative Enzyme Immunoassay




1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Random urine.

Specimen Preparation

Transfer 2 mL urine to an ARUP Standard Transport Tube.

Storage/Transport Temperature


Unacceptable Conditions

Specimens other than urine. Urine in boric acid. Serum; refer to test Histoplasma Antigen by EIA, Serum (ARUP test code 0092522).


Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Reference Interval

Not Detected

Interpretive Data

Less than 0.4 ng/ml = Not Detected
0.4-3.1 ng/mL = Detected (below the limit of quantification)
3.2-20.0 ng/mL = Detected
Greater than 20.0 ng/mL = Detected (above the limit of quantification)

The quantitative range of this assay is 3.2-20.0 ng/mL. Antigen concentrations between 0.4-3.1 or >20.0 ng/mL fall outside the linear range of the assay and cannot be accurately quantified.

This EIA test should be used in conjunction with other diagnostic procedures, including microbiological culture, histological examination of biopsy samples, and/or radiographic evidence, to aid in the diagnosis of histoplasmosis.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
CPT Codes


Component Test Code* Component Chart Name LOINC
2006111 Histoplasma Galactomannan Ag Interp, Urn 44524-7
2006112 Histoplasma Galactomannan Ag Quant, Urn 48952-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Histoplasma capsulatum
Histoplasma Galactomannan Antigen Quantitative by EIA, Urine