Ordering Recommendation

Aid in the diagnosis of histoplasmosis. Recommend testing in conjunction with Histoplasma Antigen Quantitative by EIA, Serum (0092522) and Histoplasma Galactomannan Antigen Quantitative by EIA, Urine (2009418).

Mnemonic
HISTO PAN
Methodology

Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion

Performed

Sun-Fri

Reported

3-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0050174 Histoplasma spp. Antibodies by Immunodiffusion None detected.
  Histoplasma Yeast, CF Less than 1:8
  Histoplasma Mycelia, CF Less than 1:8

Interpretive Data

Refer to individual components.

Compliance Category

FDA

Note

Negative fungal serology does not rule out the possibility of current infection.

Hotline History
N/A
CPT Codes

86698 x3

Components
Component Test Code* Component Chart Name LOINC
0050174 Histoplasma spp. Abs, Precipitin 5218-3
0050330 Histoplasma Mycelia, CF 20573-2
0050335 Histoplasma Yeast, CF 20574-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Histoplasma CF & ID
  • Histoplasma Mycelia Ab
  • Histoplasma Precipitin
  • Histoplasma spp Ab
  • Histoplasma Yeast Ab
  • Histoplasmosis Antibody
Histoplasma Antibodies by CF & ID