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High-Specificity Antiphospholipid Antibodies, IgG and IgM
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Acceptable initial test when antiphospholipid syndrome (APS) is strongly suspected. More specific than cardiolipin IgG and IgM antibodies in the diagnosis of APS.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Sun
1-8 days
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Refrigerated.
Contaminated, heat-inactivated, grossly hemolyzed, grossly icteric, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
| Test Number |
Components |
Reference Interval |
||||||
|---|---|---|---|---|---|---|---|---|
| High-Specificity Antiphospholipid Ab IgG |
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| High-Specificity Antiphospholipid Ab IgM |
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High-specificity antiphospholipid IgG and IgM antibodies are directed against a mixture of phosphatidylserine, phosphatidic acid, and beta-2 glycoprotein 1 antigens. These antibodies are more specific than cardiolipin IgG and IgM antibodies in the diagnosis of antiphospholipid syndrome (APS).
No compliance statements are in use for this test.
GPL = IgG phospholipid units; MPL = IgM phospholipid units
83516 x2
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2005458 | High-Specificity Antiphospholipid Ab IgG | 7801-4 |
| 2005459 | High-Specificity Antiphospholipid Ab IgM | 7802-2 |
- APS-HS
