Acceptable initial test when antiphospholipid syndrome (APS) is strongly suspected. More specific than cardiolipin IgG and IgM antibodies in the diagnosis of APS.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Contaminated, heat-inactivated, grossly hemolyzed, grossly icteric, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|High-Specificity Antiphospholipid Ab IgG||
|High-Specificity Antiphospholipid Ab IgM||
High-specificity antiphospholipid IgG and IgM antibodies are directed against a mixture of phosphatidylserine, phosphatidic acid, and beta-2 glycoprotein 1 antigens. These antibodies are more specific than cardiolipin IgG and IgM antibodies in the diagnosis of antiphospholipid syndrome (APS).
GPL = IgG phospholipid units; MPL = IgM phospholipid units
|Component Test Code*||Component Chart Name||LOINC|
|2005458||High-Specificity Antiphospholipid Ab IgG||7801-4|
|2005459||High-Specificity Antiphospholipid Ab IgM||7802-2|