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Time Sensitive
Ordering Recommendation

Use to monitor treatment, response, and compliance with dietary restriction for patients with an established diagnosis of galactosemia. To diagnose or rule out galactosemia, refer to Galactosemia (GALT) Enzyme Activity and 9 Mutations (0051175).

Mnemonic
GAL1P RBC
Methodology

Gas Chromatography-Mass Spectrometry (GC-MS)

Performed

Tue

Reported

2-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or green (sodium or lithium heparin).

Specimen Preparation

DO NOT FREEZE. Place tube on wet ice immediately after collection. Transport 5 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Frozen or room temperature specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable

Reference Interval
Test Number
Components
Reference Interval
  Galactose-1-phosphate (mg/dL) 0.0-1.0 mg/dL
  Galactose-1-phosphate (ug/g Hb) 0-53 ug/g Hb
  Galactose-1-phosphate (umol/g Hb) 0.00-0.20 umol/g Hb

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

Alternate acceptable specimen is frozen, washed red blood cells.
1. Centrifuge whole blood immediately for 10 minutes at 800 g RCF.
2. Discard the plasma and buffy coat layers.
3. Add cold 0.9 percent saline solution to the red cells (about 2 times the volume of cells) and mix gently by inverting the tube.
4. Centrifuge for 10 minutes at 800 g RCF.
5. Aspirate and discard the supernatant.
6. Repeat the wash (steps 3 through 5) 2 more times.
7. After the 3rd wash and centrifugation, remove the supernatant and a thin layer of the top cells. 
8. Transfer washed cells to an ARUP standard transport tube and freeze. Ship on dry ice and include an ORDER COMMENT stating the specimen is washed, packed red blood cells.
 
Washed red cells must be frozen.  Ambient and refrigerated washed cells are unacceptable

Hotline History
N/A
CPT Codes

84378

Components
Component Test Code* Component Chart Name LOINC
0081298 Galactose-1-phosphate (mg/dL) 2312-7
0081299 Galactose-1-phosphate (ug/g Hb) 33360-9
0081300 Galactose-1-phosphate (umol/g Hb) 38485-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Gal1P
  • Galactose 1
  • Galactose 1 Phosphate
  • Galactosemia Analyte
  • Galactosemia Metabolite(s)
  • GALT Analyte
  • RBC GAL1P
Galactose-1-Phosphate in Red Blood Cells