Ordering Recommendation
Confirm current or recent infection with group A Streptococcus in patients suspected of having a nonsuppurative complication such as acute glomerulonephritis (AGN) or acute rheumatic fever (ARF). DNase-B Antibody (0050220) and Streptolysin O Antibody (ASO) (0050095) are generally ordered concurrently. Preferred test for rheumatic chorea since it remains elevated longer.
Mnemonic
Methodology
Quantitative Nephelometry
Performed
Sun, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)
Refrigerated.
Plasma or severely hemolyzed specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
0-6 years: Less than 250 U/mL
7-17 years: Less than 310 U/mL
18 years and older: Less than 260 U/mL
Interpretive Data
FDA
Note
Hotline History
CPT Codes
86215
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050220 | DNAse B Antibody | 5133-4 |
Aliases
- DNase-B, Anti
- ADB (Antideoxyribonuclease B)
- Anti-Dnase B
- Anti-DNase-B Antibody
- Anti-Hyaluronidase
- Antideoxyribonuclease B (ADB)
- Antideoxyribonulease
- DNA Streptococcal Antibody
- Hyaluronidase
- Serum Dnase-B Antibody
- Streptococcal Antibodies, Serum