Pain Management Drug Panel by High-Resolution Time-of-Flight Mass Spectrometry and Enzyme Immunoassay, Urine
2007479
 
Ordering Recommendation
Mnemonic
PAIN HYB U
Methodology
Qualitative Liquid Chromatography/Time of Flight Mass Spectrometry/Enzyme Immunoassay/Quantitative Spectrophotometry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Random urine.  
Specimen Preparation
Transfer 4 mL each into two (2) ARUP Standard Transport Tubes urine with no additives or preservatives. (Min: 2 mL each)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles.  
Remarks
 
Stability
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years  
Reference Interval

Drugs covered and range of cutoff concentrations. Note that some drugs are identified based on the presence of unique drug metabolites not listed below.
Drugs/Drug Classes Range of Cutoff Concentrations
Barbiturates 200 ng/mL
Benzodiazepine-​like:
alprazolam, clonazepam, diazepam, lorazepam, midazolam, nordiazepam, oxazepam, temazepam, zolpidem
20 -​ 60 ng/mL
Cannabinoids (11-​nor-​9-​carboxy-​THC) 20 ng/mL
Ethyl Glucuronide 500 ng/mL
Muscle Relaxant(s):
carisoprodol, meprobamate
100 ng/mL
Opiates/Opioids:
buprenorphine, codeine, dihydrocodeine, fentanyl, heroin, hydrocodone, hydromorphone, meperidine, methadone, morphine, oxycodone, oxymorphone, propoxyphene, tapentadol, tramadol
2-​300 ng/mL
Phencyclidine (PCP) 25 ng/mL
Stimulants:
amphetamine, cocaine, methamphetamine, methylphenidate, MDMA (Ecstasy), MDEA (Eve), MDA, phentermine
100-​400 ng/mL
Interpretive Data
Methodology: Qualitative Enzyme Immunoassay and Qualitative Liquid Chromatography-Time-of-Flight-Mass Spectrometry, Quantitative Spectrophotometry

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration must be greater than or equal to the cutoff concentration to be reported as present. If specific drug concentrations are required, contact the laboratory within two weeks of specimen collection to request confirmation and quantification by a second analytical technique. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.
Note
Creatinine concentration is also provided. The carisoprodol assay has cross-reactivity to carisoprodol and meprobamate and cannot distinguish between the two drugs.
CPT Code(s)
80100; 80101 x8; (HCPCS: G0431).
Components
Component Test Code*Component Chart Name
0090386Creatinine, Urine
2007635OPIATES, HIGH RES URINE
2007636Codeine (cutoff 40 ng/mL)
2007637Morphine (cutoff 20 ng/mL)
20076386-acetylmorphine (cutoff 10 ng/mL)
2007639OXYCODONE-LIKE, HIGH RES URINE
2007640Oxycodone (cutoff 40 ng/mL)
2007641Noroxycodone (cutoff 100 ng/mL)
2007642Oxymorphone (cutoff 40 ng/mL)
2007643Noroxymorphone (cutoff 100 ng/mL)
2007644Hydrocodone (cutoff 40 ng/mL)
2007645Dihydrocodeine (cutoff 20 ng/mL)
2007646Norhydrocodone (cutoff 100 ng/mL)
2007647Hydromorphone (cutoff 40 ng/mL)
2007648OPIOIDS, OTHER, HIGH RES URINE
2007649Buprenorphine (cutoff 5 ng/mL)
2007650Buprenorphine-G (cutoff 200 ng/mL)
2007651Norbuprenorphine (cutoff 20 ng/mL)
2007652Fentanyl (cutoff 2 ng/mL)
2007653Norfentanyl (cutoff 2 ng/mL)
2007654Meperidine metabolite (cutoff 50 ng/mL)
2007655Tapentadol (cutoff 100 ng/mL)
2007656Tapentadol-o-Sulf (cutoff 200 ng/mL)
2007657OPIOIDS, OTHER, IMMUNOASSAY URINE
2007658Methadone (cutoff 150 ng/mL)
2007659Propoxyphene (cutoff 300 ng/mL)
2007660Tramadol (cutoff 200 ng/mL)
2007661AMPHETAMINE-LIKE, HIGH RES URINE
2007662Amphetamine (cutoff 100 ng/mL)
2007663Methamphetamine (cutoff 400 ng/mL)
2007664MDMA- Ecstasy (cutoff 200 ng/mL)
2007665MDA (cutoff 200 ng/mL)
2007666MDEA- Eve (cutoff 200 ng/mL)
2007667Ritalinic Acid (cutoff 100 ng/mL)
2007668Phentermine (cutoff 100 ng/mL)
2007669COCAINE, IMMUNOASSAY URINE
2007670Benzoylecgonine (cutoff 150 ng/mL)
2007671BENZODIAZEPINE-LIKE, HIGH RES URINE
2007672Alprazolam (cutoff 40 ng/mL)
2007673Alpha-OH-Alprazolam (cutoff 20 ng/mL)
2007674Clonazepam (cutoff 20 ng/mL)
20076757-Aminoclonazepam (cutoff 40 ng/mL)
2007676Diazepam (cutoff 50 ng/mL)
2007677Nordiazepam (cutoff 50 ng/mL)
2007678Oxazepam (cutoff 50 ng/mL)
2007679Temazepam (cutoff 50 ng/mL)
2007680Lorazepam (cutoff 60 ng/mL)
2007681Midazolam (cutoff 20 ng/mL)
2007682Zolpidem (cutoff 20 ng/mL)
2007683BARBITURATES, IMMUNOASSAY, URINE
2007684Barbiturates (cutoff 200 ng/mL)
2007685OTHERS, IMMUNOASSAY OR SPECTRO URINE
2007687Ethyl Glucuronide (cutoff 500 ng/mL)
2007688Marijuana Metabolite (cutoff 20 ng/mL)
2007689PCP (cutoff 25 ng/mL)
2007690Carisoprodol (cut-off 100 ng/mL)
2007691Pain Management Drug Panel
2008312EER Pain Mgt Drug Panel, High Res/EMIT U
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Comprehensive hybrid, TOF, high res, high-res
  • Pain management, (drug screen, targeted, urine)