Galactose-1-Phosphate in Red Blood Cells
0081296
Ordering Recommendation
Use to monitor treatment, response, and compliance with dietary restriction for patients with an established diagnosis of galactosemia. To diagnose or rule out galactosemia, refer to Galactosemia (GALT) Enzyme Activity and 9 Mutations (0051175).
Mnemonic
GAL1P RBC
Methodology
Gas Chromatography-Mass Spectrometry
Performed
Tue
Reported
2-9 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or green (sodium or lithium heparin).  
Specimen Preparation
DO NOT FREEZE. Place tube on wet ice immediately after collection. Transport 5 mL whole blood. (Min: 2 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Frozen or room temperature specimens.  
Remarks
  
Stability
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable  
Reference Interval
 
 
Test Number Components Reference Interval
 Galactose-​1-​phosphate 0.0-​1.0 mg/dL
 Galactose-​1-​phosphate (ug/g Hb) 0-​53 ug/g Hb
 Galactose-​1-​phosphate (umol/g Hb) 0.00-​0.20 umol/g Hb
Interpretive Data


See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
Alternate acceptable specimen is frozen, washed red blood cells.
1. Centrifuge whole blood immediately for 10 minutes at 800 g RCF.
2. Discard the plasma and buffy coat layers.
3. Add cold 0.9 percent saline solution to the red cells (about 2 times the volume of cells) and mix gently by inverting the tube.
4. Centrifuge for 10 minutes at 800 g RCF.
5. Aspirate and discard the supernatant.
6. Repeat the wash (steps 3 through 5) 2 more times.
7. After the 3rd wash and centrifugation, remove the supernatant and a thin layer of the top cells. 
8. Transfer washed cells to an ARUP standard transport tube and freeze. Ship on dry ice and include an ORDER COMMENT stating the specimen is washed, packed red blood cells.
 
Washed red cells must be frozen.  Ambient and refrigerated washed cells are unacceptable
CPT Code(s)
84378
Components
Component Test Code*Component Chart NameLOINC
0081298Galactose-1-phosphate (mg/dL) 
0081299Galactose-1-phosphate (ug/g Hb) 
0081300Galactose-1-phosphate (umol/g Hb) 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Gal1P
  • Galactokinase
  • Galactose 1
  • Galactose 1 Phosphate
  • Galactosemia Analyte
  • Galactosemia Metabolite(s)
  • GALT Analyte
  • RBC GAL1P