When used in conjunction with other autoantibody tests (ANCA, PR-3), may assist in evaluating suspected immune-mediated vasculitis, especially microscopic polyangiitis (MPA). May be useful when monitoring MPA disease and/or treatment response.
Panel tests are available. For the workup of suspected vasculitis, refer to ANCA-Associated Vasculitis Profile (ANCA/MPO/PR-3) Reflex to ANCA Titer (2006480). For patients with a history of vasculitis, refer to the ANCA Reflex to Titer and MPO/PR-3 Antibodies (2002068).
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Negative||19 AU/mL or less|
|Positive||26 AU/mL or greater|
|Component Test Code*||Component Chart Name||LOINC|
|0050526||Myeloperox Antibodies, IgG||6969-0|
- MPO Ab