Myeloperoxidase (MPO) Antibody and Serine Proteinase 3 (PR3) Antibody with Reflex to Anti-Neutrophil Cytoplasmic Antibody, IgG by IFA
Preferred first-line reflex panel for the evaluation of ANCA-associated vasculitis.
Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Multiplex Bead Assay
New York DOH Approval Status
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
CSF, plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|3003747||Anti-Neutrophil Cytoplasmic Antibody, IgG by IFA||
|0050526||Myeloperoxidase (MPO) Antibody||
|0050527||Serine Proteinase 3 (PR3) Antibody||
Refer to report.
If MPO and/or PR3 results are equivocal or positive, then ANCA by IFA will be added. Additional changes apply. Specimens are screened by IFA on ethanol-fixed neutrophils, formalin-fixed neutrophils, and HEp-2 slides that allow differentiation of C- and P-ANCA patterns.
83516 x 2; if reflexed, add 86255
|Component Test Code*||Component Chart Name||LOINC|
|0050526||Myeloperoxidase (MPO) Ab, IgG||6969-0|
|0050527||Serine Proteinase 3 (PR3) Ab, IgG||6968-2|
- (Perinuclear Antineutrophil Cytoplasmic Antibody
- ANCA Panel, IgG
- Anti-Neutrophil Cytoplasmic Ab Test
- Anti-Neutrophil Cytoplasmic Antibodies Panel, IgG
- Anticytoplasmic Antibody
- Antineutrophil Cytoplasmic Antibodies (ACPA)
- Autoantibodies to Proteinase 3
- c ANCA (Anti-Neutrophil Cytoplasmic Antibody with Reflex to Titer & MPO/PR3 Antibodies)
- Cytoplasmic Neutrophil Antibodies; MPO)
- p ANCA
- Proteinase 3