Red Blood Cell Antigen Genotyping
Ordering Recommendation
Use to predict the expression of red blood cell (RBC) antigen specificities, aid in the selection of antigen-negative RBCs for transfusion, assess the risk of alloimmune hemolytic disease, or resolve conflicting serologic antibody results. For fetal testing, order Red Blood Cell Antigen Genotyping, Fetal (3016639) using a fetal specimen. This test does not assess for RhD; to test for RhD, refer to RhD Gene (RHD) Copy Number (0051368).
New York DOH Approval Status
Specimen Required
Lavender (EDTA), pink (K2EDTA).
Transport 3 mL whole blood. (Min: 1 mL)
Refrigerated
Yellow (ACD solution A or B); plasma or serum. Collection of specimens in sodium heparin tubes. Frozen specimens in glass collection tubes.
Patient History Form is available on the ARUP website or by contacting ARUP Client Services.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month.
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring
Performed
Varies
Reported
3-10 days
Reference Interval
Interpretive Data
Refer to report.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
FDA
Note
Hotline History
Hotline History
CPT Codes
0001U
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001054 | RBC Antigen Genotyping Specimen | 31208-2 |
3001055 | Rh Antigen C/c | |
3001056 | Rh Antigen E/e | |
3001057 | Rh Antigen V/VS | |
3001058 | Kell Antigen K/k | |
3001059 | Kell Antigen Kpa/Kpb | |
3001060 | Kell Antigen Jsa/Jsb | |
3001061 | Duffy Antigen Fya/Fyb | |
3001062 | Kidd Antigen Jka/Jkb | |
3001063 | MNS Antigen MN | |
3001064 | MNS Antigen S/s/U | |
3001065 | Lutheran Antigen Lua/Lub | |
3001066 | Dombrock Antigen Doa/Dob | |
3001067 | Dombrock Antigen Hy | |
3001068 | Dombrock Antigen Joa | |
3001069 | Landsteiner-Wiener Antigen LWa/LWb | |
3001070 | Diego Antigen Dia/Dib | |
3001071 | Colton Antigen Coa/Cob | |
3001072 | Scianna Antigen Sc1/Sc2 | |
3001073 | Hemoglobin S Antigen | |
3001074 | RBC Antigen Genotyping Interpretation | 50398-7 |
Aliases
- Colton genotyping (Coa, Cob)
- Diego genotyping (Dia, Dib)
- Dombrock genotyping (Doa, Dob, Hy, Joa)
- Duffy genotyping (Fya, Fyb, Fyb-67C)
- Kell genotyping (K, k, Kpa, Kpb, Jsa, Jsb)
- Kidd genotyping (Jka, Jkb)
- Landsteiner-Wiener genotyping (LWa, LWb)
- Lutheran genotyping (Lua, Lub)
- MNS genotyping (M, N, S, s, U, Uvar, Uneg)
- Rh genotyping (C, c, E, e, V, VS)
- Scianna genotyping (Sc1, Sc2)