Ordering Recommendation

Comprehensive genetic test to detect alpha thalassemia or alpha thalassemia trait. For fetal testing, refer to Alpha Globin (HBA1 and HBA2) Sequencing and Deletion/Duplication, Fetal (3019566).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Frozen specimens

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 month; Frozen: unacceptable

Methodology

Multiplex Ligation-Dependent Probe Amplification (MLPA) / Sequencing / Polymerase Chain Reaction (PCR)

Performed

Varies

Reported

14-21 days

Reference Interval

Refer to report

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

When testing cord blood specimens, the presence of maternal cell contamination (MCC) is possible, which may impact result interpretation. If clinically warranted, testing for MCC is available, at a charge, through ARUP Laboratories.

Hotline History

N/A

CPT Codes

81259; 81269

Components

Component Test Code* Component Chart Name LOINC
2011709 HBA Seq, Del/Dup Specimen 66746-9
2011710 HBA Seq, Del/Dup Interp 35474-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Alpha Globin ( HBA1 and HBA2 ) Sequencing and Deletion/Duplication