3021476
print

Copper and Zinc, Serum or Plasma

CUZN S

Ordering Recommendation

Use to assess copper deficiency or overload. This test measures both protein-bound and free forms of copper in serum or plasma. May be useful as an indicator of acute zinc deficiency. For acute toxicity, Zinc, Urine (0020462) may be a more reliable indicator for exposure.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications for one week prior to sample draw (upon the advice of their physician).

Collect

Royal blue (no additive), royal blue (K2EDTA), or royal blue (NaHep).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116) available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at 800-522-2787 (Min: 0.5 mL). Do not use utensils (i.e., syringes, needles) during the transfer of the sample. Carefully pour directly into the transport tube avoiding transfer of the cellular components of blood.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated or frozen.

Unacceptable Conditions

Specimens that are not separated from the red cells or clot within 2 hours. Specimens collected in containers other than specified. Specimens transported in containers other than specified. Hemolyzed specimens.

Remarks
Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

82525, 84630

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0020096 Copper, Serum/Plasma 5631-7
0020097 Zinc, Serum/Plasma 5763-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Copper Plasma
  • Cu
  • Cu, Plasma
  • CUS
  • Kaiser Fleischer Ring
  • total blood copper level
  • Wilson disease
  • serum zinc level
  • Zn
  • ZNS
Copper and Zinc, Serum or Plasma