Platelet Antigen Genotyping Panel, Fetal
Ordering Recommendation
Fetal genotyping to assess risk for alloimmune thrombocytopenia. For parental or neonatal testing, refer to Platelet Antigen Genotyping Panel (3000193).
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis
Performed
Varies
Reported
7-14 days
New York DOH Approval Status
Specimen Required
Fetal genotyping: Amniotic fluid
Cultured amniocytes: Two T-25 flasks at 80 percent confluency.
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.
AND Maternal cell contamination specimen: Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container. (Min: 5 mL)
OR Cultured amniocytes: Transport two T-25 flasks at 80 percent confluency filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Maternal cell contamination specimen: Transport 3 mL whole blood. (Min: 1 mL)
Whole blood (parental genotyping): Transport 3 mL whole blood. (Min: 1 mL)
Amniotic fluid, cultured amniocytes: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood or maternal cell contamination specimen: Refrigerated.
Frozen specimens in glass collection tubes.
Fetal specimens Amniotic fluid or cultured amniocytes: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Whole blood or maternal cell contamination specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Reference Interval
Interpretive Data
Refer to report.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Modified FDA
Note
Please submit maternal specimen if amniotic fluid is bloody. Maternal specimen is recommended for proper test interpretation; order Maternal Cell Contamination, Maternal Specimen.
Hotline History
Hotline History
CPT Codes
81105; 81106; 81107; 81108; 81109; 81110; 81112; 81265 Fetal Cell Contamination (FCC)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050548 | Maternal Contamination Study Fetal Spec | 59266-7 |
0050612 | Maternal Contam Study, Maternal Spec | 66746-9 |
3001173 | Platelet Antigen 1 Genotyping | |
3001174 | Platelet Antigen 2 Genotyping | |
3001175 | Platelet Antigen 3 Genotyping | |
3001176 | Platelet Antigen 4 Genotyping | |
3001177 | Platelet Antigen 5 Genotyping | |
3001178 | Platelet Antigen 6 Genotyping | |
3001179 | Platelet Antigen 15 Genotyping | |
3016674 | Platelet Antigen Geno Fetal, Interp | |
3016675 | Platelet Antigen Geno, Fetal Specimen |
Aliases
- HPA platelet antigen genotyping panel