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Leukotriene E4, 24-Hour Urine
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Ordering Recommendation
Aids in the initial evaluation of suspected cases of mast cell activation disorders. A 24-hour urine collection is preferred. If submitting random urine, order Leukotriene E4, Random Urine (3002351).
Mnemonic
Methodology
Quantitative Colorimetry/Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Performed
Varies
Reported
3-9 days
New York DOH Approval Status
Specimen Required
Patients taking 5-lipoxygenase inhibitor Zileuton/Zyflo may have decreased concentrations of leukotriene E4 (LTE4). If possible, discontinue 48 hours prior to collection.
24-hour urine. Refrigerate during collection.
From a well-mixed 24-hour collection transfer 5 mL urine to ARUP Standard Transport Tubes (Min: 2 mL).
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Refrigerated. Also acceptable: Frozen
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
Reference Interval
By Report
Interpretive Data
Performed by non-ARUP Laboratory
Note
Hotline History
Hotline History
CPT Codes
82542
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3004163 | Creatinine, 24 Hour Urine | |
| 3004164 | Collection Duration: | |
| 3004165 | Urine Volume: | |
| 3004166 | Creatinine Concentration, 24 Hour Urine | |
| 3004793 | Leukotriene E4, 24 Hour Urine | 33343-5 |
Aliases
- Cysteinyl Leukotriene
- LTE4
- Mastocytosis
- Systemic mast Cell Activation
Mayo Clinic Laboratories
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