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Circulating Immune Complex, C3 fragments
Ordering Recommendation
Use to detect circulating immune complexes. Consider ordering Circulating Immune Complex Panel (3004430), which contains both Circulating Immune Complex, C3 Fragments and Circulating Immune Complex, C1q Binding assays.
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST).
Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately. Transport 1 mL serum. (Min: 0.5 mL) If ordered in conjunction with a C1q Binding Assay, transfer TWO (2) 1 mL aliquots of serum to individual ARUP Standard Transport Tubes.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Grossly hemolyzed, lipemic, and icteric specimens.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 20 days
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Thu, Sat
Reported
2-9 days
Reference Interval
Less than or equal to 15 µg Eq/mL
Interpretive Data
Many autoimmune disorders, chronic infections, and malignancies are associated with circulating immune complexes. Quantitation of immune complexes assists in staging immunologic disorders. Detection of circulating immune complexes is not essential to any specific diagnosis. Circulating immune complexes may be found without any evident pathology and positive results do not necessarily implicate immune complex-related disease process. Values between 15 and 20 ug Eq/mL are considered equivocal for the Circulating Immune Complex, C3 fragments assay. Repeat testing using a new specimen is recommended, if clinically indicated
FDA
Note
Hotline History
CPT Codes
86332
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3004432 | Circulating Immune Complex, C3 fragments | 5228-2 |
Aliases
- Immune Complex Assay
