Use to detect circulating immune complexes.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Saturday, Monday, Thursday
New York DOH Approval Status
Plain red or serum separator tube (SST).
Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately. Transfer TWO (2) 1 mL aliquots of serum to individual ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Grossly hemolyzed, lipemic, and icteric specimens.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks
Many autoimmune disorders, chronic infections, and malignancies are associated with circulating immune complexes. Quantitation of immune complexes assists in staging immunologic disorders. Detection of circulating immune complexes is not essential to any specific diagnosis. Circulating immune complexes may be found without any evident pathology and positive results do not necessarily implicate immune complex-related disease process. Values between 15 and 20 ug Eq/mL are considered equivocal for the Circulating Immune Complex, C3 fragments assay. Repeat testing using a new specimen is recommended, if clinically indicated.
|Component Test Code*||Component Chart Name||LOINC|
|0050301||Circulating Immune Complex, C1q Binding||27831-7|
|3004432||Circulating Immune Complex, C3 fragments||5228-2|
- C1q binding Immune Complexes
- C1q binding; CIC
- C3 fragment containing immune complexes
- CIC-Raji Cell Replacement assay
- Circulating Immune Complex Panel