APC- and MUTYH-Associated Polyposis Panel, Sequencing and Deletion/Duplication
Recommended diagnostic or predictive test for APC-associated polyposis conditions (familial adenomatous polyposis [FAP], attenuated FAP, gastric adenocarcinoma and proximal polyposis of the stomach [GAPPS]) and MUTYH-associated polyposis (MAP). Testing minors for adult-onset conditions is not recommended; testing will not be performed in minors without prior approval. For additional information, please contact an ARUP genetic counselor at 800-242-2787 ext. 2141.
To compare this test to other hereditary cancer panels, refer to the Hereditary Cancer Panel Comparison table.
Massively Parallel Sequencing
New York DOH Approval Status
Lavender or Pink (EDTA) or Yellow (ACD Solution A or B).
Transport 3 mL whole blood. (Min: 3 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva; buccal brush or swab, FFPE tissue.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report
Laboratory Developed Test (LDT)
Genes Tested: APC (NM_000038, NM_001127511 Exon 1b only), MUTYH (NM_001128425)
81201; 81203; 81406; 81479
|Component Test Code*||Component Chart Name||LOINC|
- familial adenomatous polyposis
- Gardner syndrome
- Turcot syndrome