Ordering Recommendation
Preferred diagnostic or predictive test for APC-associated polyposis conditions (familial adenomatous polyposis [FAP], attenuated FAP, gastric adenocarcinoma and proximal polyposis of the stomach [GAPPS]) and MUTYH-associated polyposis (MAP).
Mnemonic
APCMYH NGS
Methodology
Massively Parallel Sequencing
Performed
Varies
Reported
3 weeks
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect
Lavender or Pink (EDTA) or Yellow (ACD Solution A or B).
Specimen Preparation
Transport 3 mL whole blood. (Min: 3 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Serum or plasma; grossly hemolyzed or frozen specimens; saliva; buccal brush or swab, FFPE tissue.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
Refer to report
Compliance Category
Note
Genes Tested: APC (NM_000038, NM_001127511 Exon 1b only), MUTYH (NM_001128425)
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
81201; 81203; 81406; 81479
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3004408 | APCMYH Specimen | 66746-9 |
3004409 | APCMYH Interp | 35474-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- AFAP
- familial adenomatous polyposis
- FAP
- GAPPS
- Gardner syndrome
- MAP
- MYH
- Turcot syndrome
APC- and MUTYH-Associated Polyposis Panel, Sequencing and Deletion/Duplication