Ordering Recommendation

Limited phenotyping panel, using peripheral blood or bone marrow, to enumerate and characterize chronic lymphocytic leukemia cells (CD5+ monoclonal B-cells) in patients with previously established diagnosis of CLL. If no prior flow immunophenotyping has been performed, order Leukemia/Lymphoma Phenotyping Evaluation by Flow Cytometry (3001780).

New York DOH Approval Status

This test is not New York state approved. Due to short specimen stability it is recommended that this testing be submitted directly to a New York state-approved laboratory. Do not submit sample to ARUP.

Specimen Required

Patient Preparation
Collect

Whole blood or bone marrow in green (sodium heparin), lavender (K2EDTA)

Specimen Preparation

Transport 3 mL whole blood or bone marrow. (Min: 1 mL) Do not freeze.

Storage/Transport Temperature

Room temperature. Also, acceptable: Refrigerated. Specimen should be received within 24 hours of collection for optimal cell viability.

Unacceptable Conditions
Remarks
Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Methodology

Flow Cytometry

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

88184; 88185 x9; 88188

Components

Component Test Code* Component Chart Name LOINC
3003143 Interpretation 45266-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • chronic lymphocytic leukemia cells (CD5+ monoclonal B-cells)
  • CLL MRD
  • high sensitivity CLL testing
Chronic Lymphocytic Leukemia Minimum Residual Disease by Flow Cytometry