Ordering Recommendation

Limited phenotyping panel, using peripheral blood or bone marrow, to enumerate and characterize chronic lymphocytic leukemia cells (CD5+ monoclonal B-cells) in patients with previously established diagnosis of CLL. If no prior flow immunophenotyping has been performed, order Leukemia/Lymphoma Phenotyping Evaluation by Flow Cytometry (3001780).

Mnemonic
CLL MRD
Methodology

Flow Cytometry

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Whole Blood or Bone Marrow in Green (Sodium Heparin), Lavender (K2EDTA)

Specimen Preparation

Transport 3 mL Whole Blood or Bone Marrow. (Min: 1 mL) Do not freeze.

Storage/Transport Temperature

Room temperature. Also, acceptable: Refrigerated. Specimen should be received within 24 hours of collection for optimal cell viability.

Unacceptable Conditions
Remarks
Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Reference Interval
Interpretive Data

Refer to report.

Compliance Category
Note
Hotline History
N/A
CPT Codes

88184; 88185 x9; 88188

Components
Component Test Code* Component Chart Name LOINC
3003143 Interpretation 45266-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • chronic lymphocytic leukemia cells (CD5+ monoclonal B-cells)
  • CLL MRD
  • high sensitivity CLL testing
Chronic Lymphocytic Leukemia Minimum Residual Disease by Flow Cytometry