Ordering Recommendation

Aids in the diagnosis of coccidioidal meningitis. For comprehensive diagnostic testing that includes immunoassay (IgM and IgG), complement fixation, and immunodiffusion, refer to Coccidioides Antibodies Panel, CSF (3000061).

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation


Specimen Preparation

Transfer 2 mL CSF to an ARUP Standard Transport Tube. (Min: 1 mL). Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature


Unacceptable Conditions

Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.


Mark specimens plainly as "acute" or "convalescent".


Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)


Complement Fixation/Immunodiffusion




2-6 days

Reference Interval

Test Number
Reference Interval
  Coccidioides by Immunodiffusion, CSF None detected.
  Coccidioides Ab by CF, CSF Less than 1:2

Interpretive Data

Refer to report.

Compliance Category

Modified FDA


The immunodiffusion component of this test uses culture filtrates of Coccidioides immitis and includes CF and TP antigens.

Hotline History


CPT Codes

86635 x2


Component Test Code* Component Chart Name LOINC
0050711 Coccidioides Ab by CF, CSF 13917-0
3000064 Coccidioides by Immunodiffusion, CSF 21209-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • CF
  • Coccidioides immitis
  • Coccidioidomycosis
  • TP
  • Valley fever
Coccidioides Antibodies by Complement Fixation and Immunodiffusion, CSF