Ordering Recommendation

Aids in the diagnosis of coccidioidomycosis. Includes testing by complement fixation and immunodiffusion. For comprehensive diagnostic testing that includes immunoassay (IgM and IgG), complement fixation, and immunodiffusion, refer to Coccidioides Antibodies Panel, Serum (0050588).

Mnemonic

COCC.CFIDS

Methodology

Complement Fixation/Immunodiffusion

Performed

Sun-Sat

Reported

2-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL). Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.

Remarks

Mark specimens plainly as "acute" or "convalescent".

Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective May 16, 2022

Test Number
Components
Reference Interval
  Coccidioides by Immunodiffusion, Serum Not detected.
0050170 Coccidioides Antibodies by Complement Fixation Less than 1:2

Interpretive Data

Refer to report

Compliance Category

FDA

Note

This immunodiffusion test uses culture filtrates of Coccidioides immitis and includes CF and TP antigens.

Hotline History

N/A

CPT Codes

86635 x2

Components

Component Test Code* Component Chart Name LOINC
0050170 Coccidioides Antibody by CF 33380-7
0050183 Coccidioides by Immunodiffusion, Serum 5095-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • CF
  • Coccidioides immitis
  • Coccidioidomycosis
  • Precipitin
  • TP
  • Valley fever
Coccidioides Antibodies by Complement Fixation and Immunodiffusion, Serum