Preferred test is Coccidioides Antibody Reflexive Panel (3001982).
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion
New York DOH Approval Status
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer two 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Other body fluids. Hemolyzed, icteric, or lipemic specimens.
Mark specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Test Number||Components||Reference Interval|
|0050183||Coccidioides Antibody by ID||None detected.|
|0050170||Coccidioides Antibody by CF||Less than 1:2|
Refer to report
For Coccidioides, immunodiffusion (ID) measures IgM antibody, while complement fixation (CF) measures both IgG and IgM. ELISA tests can be used to detect both coccidioidal IgG and IgM antibodies. While elevated single antibody titers may be diagnostic, paired specimens are preferred. Acute and convalescent specimens (drawn at least 21 days apart) showing a fourfold or greater rise in titer are diagnostic.
Negative fungal serology does not rule out the possibility of current infection.
|Component Test Code*||Component Chart Name||LOINC|
|0050170||Coccidioides Antibody by CF||33380-7|
|0050183||Coccidioides immitis Abs, Precipitin||5095-5|
- Cocci Antibodies Panel
- COCCI CF,ID,ELISA
- Coccidioides Antibodies Serum panel
- San Joaquin Fever Antibodies
- Valley Fever Antibodies