Ordering Recommendation
Aids in diagnosis of stiff-person syndrome, limbic encephalitis, and other autoimmune neurologic disorders. May be used in monitoring treatment response in individuals who are antibody positive. For analysis in serum, refer to Glutamic Acid Decarboxylase Antibody (2001771).
Mnemonic
Methodology
Semi-quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Fri
Reported
1-3 days
New York DOH Approval Status
Specimen Required
Cerebral Spinal Fluid (CSF)
Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen
Fluid other than CSF. Grossly hemolyzed specimens.
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 3 months
Reference Interval
0.0-5.0 IU/mL
Interpretive Data
A value greater than 5.0 IU/mL is considered positive for glutamic acid decarboxylase antibody (GAD AB CSF).
This assay is intended for the semi-quantitative determination of the GAD Ab in human CSF. Results should be interpreted within the context of clinical symptoms.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
86341
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3002789 | Glutamic Acid Decarboxylase Antibody CSF | 42501-7 |
Aliases
- 64K Antibody
- Anti-GAD Antibodies
- Anti-Glutamic Acid Decarboxylase Ab
- Beta Cell Antibody
- Beta-Cell Autoantibody to GAD 65
- GAD Antibody
- GAD CSF
- GAD Spinal Fluid
- GAD-65
- GAD65
- GAD65 Antibody Assay
- Glutamate Decarboxylase Antibodies
- Glutamic Acid Decarboxylase CSF
- Glutamic Acid Decarboxylase Spinal Fluid
- Pancreatic Islet Cell Ab