Useful in combination with Factor VIII, Activity (0030095) for the initial diagnosis of mild hemophilia A. May also be used to measure factor VIII activity in the presence of a lupus anticoagulant. Monitor certain extended half-life factor VIII replacement products and measure native factor VIII or factor VIII concentrates in patients on emicizumab (Hemlibra).
Mon, Wed, Fri
Light Blue (Sodium Citrate). Special Specimen Collection and Handling Hemostasis/Thrombosis Specimens guide located at https://www.aruplab.com/Specimen-Handling/SpecialSpecimenCollection/Hemostasis-Thrombosis.pdf
Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.8 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Serum or EDTA plasma. Clotted or hemolyzed specimens.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20° C: 3 months; Frozen at -70° C: 6 months
|0-6 years||56-191 percent|
|7-9 years||76-199 percent|
|10-11 years||80-209 percent|
|12-13 years||72-198 percent|
|14-15 years||69-237 percent|
|16-17 years||63-221 percent|
|18 years and older||56-191 percent|
Information on the clinical uses of chromogenic FVIII activity testing can be found at arupconsult.com.
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
|Component Test Code*||Component Chart Name||LOINC|
|3002344||Chromogenic Factor VIII, Activity||49865-9|
- ADYNOVATE, AFSTYLA, ELOCTATE
- AHF chromogenic
- Antihemophilic Factor (AHF) chromogenic
- Coagulation Factor VIII Chromogenic activity assay, plasma
- Factor VIII activity, chromogenic
- Factor VIII chromogenic assay
- Factor VIII:C chromogenic
- Hemlibra; emicizumab, extended half-life factor VIII products