Factor VIII, Activity
Ordering Recommendation
Use to diagnose hemophilia A or acquired factor VIII deficiency, or as part of a diagnostic workup for von Willebrand disease (VWD). May also be used to monitor treatment in individuals with factor VIII deficiency or VWD. Not recommended when screening for thrombophilia.
New York DOH Approval Status
Specimen Required
Light blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Transfer 2 mL platelet-poor plasma to an ARUP standard transport tube. (Min: 1 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Serum. EDTA plasma, clotted or hemolyzed specimens.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20° C: 3 months; Frozen at -70° C: 6 months
Methodology
Electromagnetic Mechanical Clot Detection
Performed
Mon-Sat
Reported
1-3 days
Reference Interval
Age | Reference Interval |
---|---|
0-6 years | 56-191% |
7-9 years | 76-199% |
10-11 years | 80-209% |
12-13 years | 72-198% |
14-15 years | 69-237% |
16-17 years | 63-221% |
18 years and older | 56-191% |
Interpretive Data
Standard
Note
Hotline History
CPT Codes
85240
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0030095 | Factor VIII, Activity | 3209-4 |
Aliases
- AHF
- Antihemophilic Factor (AHF), Factor VIII:C (Coagulant Portion)
- Factor VIII Activity Assay
- Intrinsic Factor Proteins
- Intrinsic Factors