Detect low-risk HPV subtypes. Preferred test to determine potential cancer risk is Human Papillomavirus (HPV) High Risk by in situ Hybridization, Paraffin (3002008).
In situ Hybridization
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 5 unstained positively charged, 5-micron slides in a tissue transport kit (recommended but not required) (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Frozen specimens.
Include surgical pathology report.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Refer to report.
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
|Component Test Code*||Component Chart Name||LOINC|
|2002895||HPV Low Risk ISH Comment||48767-8|
|2002999||ISH Tissue Source||31208-2|
|2003001||H and E Slide Description||19772-3|
|2003008||HPV ISH Low Risk|
- HPV Low Risk ISH
- HPV LR ISH
- HPVLOW ISH
- Human Papillomavirus
- low-risk HPV ISH
- LR-HPV ISH