Preferred in situ hybridization test to detect high-risk HPV subtypes to determine potential cancer risk.
In situ Hybridization
Must be in the lab by noon to make that days run.
Formalin fix (10 percent neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5-micron slides in a tissue transport kit (recommended but not required) (ARUP supply #47808). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.
Room temperature or refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Frozen specimens. Decalcified specimens.
Include surgical pathology report.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Refer to report.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2002898||HPV High Risk ISH Comment||48767-8|
|2002999||ISH Tissue Source||31208-2|
|2003001||H and E Slide Description||19772-3|
|2003006||HPV ISH High Risk|
- high-risk HPV ISH
- HPV High Risk ISH
- HPV HR ISH
- HPVHI ISH
- HR-HPV ISH