Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
Preferred in situ hybridization test to detect high-risk HPV subtypes to determine potential cancer risk.
MnemonicUnique test identifier.
HPVHR ISH
MethodologyProcess(es) used to perform the test.
In situ Hybridization
PerformedDays of the week the test is performed.
Mon-Fri
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
2-5 days Must be in the lab by noon to make that days run.
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Tissue.
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5-micron slides in a tissue transport kit (recommended but not required) (ARUP supply #47808). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.
Unacceptable Conditions
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Frozen specimens. Decalcified specimens.
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
high-risk HPV ISH
HPV
HPV High Risk ISH
HPV HR ISH
HPVHI ISH
HR-HPV ISH
Human Papillomavirus (HPV) High Risk by in situ Hybridization, Paraffin
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