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Coccidioides Antibodies Reflexive Panel, Serum

COCCI R
Example Reports
Negative
Positive

Ordering Recommendation

Aids in the diagnosis of coccidioidomycosis. Includes screening by immunoassay (IgM and IgG) and confirmation by complement fixation and immunodiffusion. For comprehensive nonreflex testing, refer to Coccidioides Antibodies Panel, Serum (0050588).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL). Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.

Remarks

Mark specimens plainly as "acute" or "convalescent".

Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Complement Fixation/Immunodiffusion/Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Sun-Sat

Reported

1-6 days

Reference Interval

Test Number
 Components
 Reference Interval
  Coccidioides Antibody, IgM by ELISA 0.9 IV or less
  Coccidioides Antibody, IgG by ELISA 0.9 IV or less

Interpretive Data




Component Interpretation
Coccidioides Antibodies, IgG by Immunoassay, Serum 0.9 IV or less   Negative - No significant level of Coccidioides IgG antibody detected.
1.0-1.4 IV  Equivocal - Questionable presence of Coccidioides IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greater  Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection.
Coccidioides Antibodies, IgM by Immunoassay, Serum 0.9 IV or less  Negative - No significant level of Coccidioides IgM antibody detected.
1.0-1.4 IV  Equivocal - Questionable presence of Coccidioides IgM antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greater  Positive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection.

Compliance Category

FDA

Note

Coccidioides Antibodies, IgM and IgG by Immunoassay, Serum is used to screen for coccidioidal antibodies. If the immunoassay testing is equivocal or positive for IgM and/or IgG, then Coccidioides Antibodies by Immunodiffusion and Coccidioides Antibody Titer by Complement Fixation, Serum will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86635 x2; if reflexed add 86635 x2

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Components

Component Test Code* Component Chart Name LOINC
0050178 Coccidioides Antibody, IgM by ELISA 90448-2
0050179 Coccidioides Antibody, IgG by ELISA 27009-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Valley fever
  • CF
  • Coccidioides immitis
  • Coccidioidomycosis
  • Precipitin
  • TP
Coccidioides Antibodies Reflexive Panel, Serum