May be useful for the evaluation of patients with progressive proximal muscle weakness and/or cutaneous manifestations suggestive of dermatomyositis and/or associated connective tissue disease.
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay/Qualitative Immunoblot
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer two 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|0099592||Jo-1 Antibody, IgG||
|Mi-2 (nuclear helicase protein) Antibody||Negative|
|PL-7 (threonyl-tRNA synthetase) Antibody||Negative|
|PL-12 (alanyl-tRNA synthetase) Antibody||Negative|
|EJ (glycyl-tRNA synthetase) Antibody||Negative|
|SRP (Signal Recognition Particle) Ab||Negative|
|OJ (isoleucyl-tRNA synthetase) Antibody||Negative|
|SAE1 (SUMO activating enzyme) Ab||Negative|
|MDA5 (CADM-140) Ab||Negative|
|NXP2 (Nuclear matrix protein-2) Ab||Negative|
|TIF-1 gamma (155 kDa) Ab||Negative|
Refer to report.
Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma
83516 x11; 86235
|Component Test Code*||Component Chart Name||LOINC|
|0099592||Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG||33571-1|
|2010852||Mi-2 (nuclear helicase protein) Antibody||18485-3|
|2010853||PL-7 (threonyl-tRNA synthetase) Antibody||33772-5|
|2010854||PL-12 (alanyl-tRNA synthetase) Antibody||33771-7|
|2010856||EJ (glycyl-tRNA synthetase) Antibody||45149-2|
|2010859||SRP (Signal Recognition Particle) Ab||33921-8|
|2010860||OJ (isoleucyl-tRNA synthetase) Antibody||45152-6|
|2013997||Myositis Interpretive Information||48767-8|
|3001786||SAE1 (SUMO activating enzyme) Ab||82440-9|
|3001787||MDA5 (CADM-140) Ab||82424-3|
|3001788||NXP2 (Nuclear matrix protein-2) Ab||82426-8|
|3001789||TIF-1 gamma (155 kDa) Ab||82448-2|