May be useful for the evaluation of patients with progressive proximal muscle weakness and/or cutaneous manifestations suggestive of dermatomyositis and/or associated connective tissue disease.
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay/Qualitative Immunoblot
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer two 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|0099592||Jo-1 Antibody, IgG||
|Mi-2 (nuclear helicase protein) Antibody||Negative|
|PL-7 (threonyl-tRNA synthetase) Antibody||Negative|
|PL-12 (alanyl-tRNA synthetase) Antibody||Negative|
|EJ (glycyl-tRNA synthetase) Antibody||Negative|
|SRP (Signal Recognition Particle) Ab||Negative|
|OJ (isoleucyl-tRNA synthetase) Antibody||Negative|
|SAE1 (SUMO activating enzyme) Ab||Negative|
|MDA5 (CADM-140) Ab||Negative|
|NXP2 (Nuclear matrix protein-2) Ab||Negative|
|TIF-1 gamma (155 kDa) Ab||Negative|
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma
83516 x7; 84182 x4; 86235
|Component Test Code*||Component Chart Name||LOINC|
|0099592||Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG||33571-1|
|2010852||Mi-2 (nuclear helicase protein) Antibody||18485-3|
|2010853||PL-7 (threonyl-tRNA synthetase) Antibody||33772-5|
|2010854||PL-12 (alanyl-tRNA synthetase) Antibody||33771-7|
|2010856||EJ (glycyl-tRNA synthetase) Antibody||45149-2|
|2010859||SRP (Signal Recognition Particle) Ab||33921-8|
|2010860||OJ (isoleucyl-tRNA synthetase) Antibody||45152-6|
|2013997||Myositis Interpretive Information||48767-8|
|3001786||SAE1 (SUMO activating enzyme) Ab||82440-9|
|3001787||MDA5 (CADM-140) Ab||82424-3|
|3001788||NXP2 (Nuclear matrix protein-2) Ab||82426-8|
|3001789||TIF-1 gamma (155 kDa) Ab||82448-2|