Dermatomyositis Autoantibody Panel

3001782
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Negative
Positive

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Additional Technical Information
Ordering Recommendation

May be useful for evaluation of patients with characteristic cutaneous manifestations of dermatomyositis with or without muscle weakness.

Mnemonic
DERM PAN
Methodology

Qualitative Immunoprecipitation/Qualitative Immunoblot

Performed

Sun-Sat

Reported

7-18 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer one 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval
Test Number
 Components
 Reference Interval
  Mi-2 (nuclear helicase protein) Antibody Negative
  P155/140 Antibody Negative
  SAE1 (SUMO activating enzyme) Ab Negative
  MDA5 (CADM-140) Ab Negative
  NXP2 (Nuclear matrix protein-2) Ab Negative
  TIF-1 gamma (155 kDa) Ab Negative

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Antibodies: Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/16/2020
X
08/19/2019
X
N/A
CPT Codes

83516 x2; 84182 x4

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Components
Component Test Code* Component Chart Name LOINC
2010852 Mi-2 (nuclear helicase protein) Antibody 18485-3
2010855 P155/140 Antibody
2013996 Dermatomyositis Interpretive Information 48767-8
3001786 SAE1 (SUMO activating enzyme) Ab 82440-9
3001787 MDA5 (CADM-140) Ab 82424-3
3001788 NXP2 (Nuclear matrix protein-2) Ab 82426-8
3001789 TIF-1 gamma (155 kDa) Ab 82448-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Dermatomyositis Autoantibody Panel