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Dermatomyositis Autoantibody Panel
Ordering Recommendation
May be useful for evaluation of patients with characteristic cutaneous manifestations of dermatomyositis with or without muscle weakness.
Methodology
Qualitative Immunoprecipitation/Qualitative Immunoblot
Performed
Sun-Sat
Reported
7-18 days
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer one 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Refrigerated
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Mi-2 (nuclear helicase protein) Antibody | Negative | |
| P155/140 Antibody | Negative | |
| SAE1 (SUMO activating enzyme) Ab | Negative | |
| MDA5 (CADM-140) Ab | Negative | |
| NXP2 (Nuclear matrix protein-2) Ab | Negative | |
| TIF-1 gamma (155 kDa) Ab | Negative |
Interpretive Data
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Antibodies: Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma
Hotline History
CPT Codes
83516 x2; 84182 x4
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2010852 | Mi-2 (nuclear helicase protein) Antibody | 18485-3 |
| 2010855 | P155/140 Antibody | 8061-4 |
| 2013996 | Dermatomyositis Interpretive Information | 48767-8 |
| 3001786 | SAE1 (SUMO activating enzyme) Ab | 82440-9 |
| 3001787 | MDA5 (CADM-140) Ab | 82424-3 |
| 3001788 | NXP2 (Nuclear matrix protein-2) Ab | 82426-8 |
| 3001789 | TIF-1 gamma (155 kDa) Ab | 82448-2 |
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